Precision Health Clinical Trials

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Conditions:   Locally Advanced Leiomyosarcoma;   Metastatic Leiomyosarcoma;   Stage III Uterine Corpus Leiomyosarcoma AJCC v8;   Stage IV Uterine Corpus Leiomyosarcoma AJCC v8;   Unresectable Leiomyosarcoma;   Uterine Corpus Leiomyosarcoma
Interventions:   Drug: Olaparib;   Drug: Pazopanib;   Drug: Temozolomide;   Drug: Trabectedin
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

Establishment of Molecular Classification Models for Early Diagnosis of Digestive System Cancers

Conditions:   Esophageal Cancer;   Gastric (Stomach) Cancer;   Colorectal Cancer;   Hepatocellular Carcinoma
Intervention:  
Sponsors:   Singlera Genomics Inc.;   Fudan University;   Shanghai Public Health Clinical Center;   Xuhui Central Hospital, Shanghai;   Shanghai Zhongshan Hospital
Recruiting

Clinical Trial Multi-analyte Blood Test

Condition:   Liver Cirrhosis
Intervention:   Diagnostic Test: Multi-analyte blood Test
Sponsor:   Helio Genomics
Recruiting

Multi-analyte Blood Test Clinical Trial

Conditions:   Liver Cirrhosis;   Liver Cancer;   HCC;   Hepatocellular Carcinoma
Intervention:   Diagnostic Test: Multi-analyte Blood Test
Sponsor:   Helio Genomics
Not yet recruiting

Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

Conditions:   Cancer;   Liver Cirrhosis;   Chronic Hepatitis;   Hepatitis B;   Hepatitis C;   Diabetes;   COPD
Intervention:   Diagnostic Test: Multi-analyte Blood Test
Sponsor:   Helio Genomics
Recruiting

Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in MDS

Conditions:   Whole Genome Sequencing;   Myelodysplastic Syndromes
Intervention:   Device: ChromoSeq
Sponsor:   Washington University School of Medicine
Not yet recruiting

Assessment the Cancer Risk of Indeterminate Thyroid Nodules Through Integration of Clinical, Ultrasonographic and Multiomic Features

Conditions:   Thyroid Nodule;   Thyroid Cancer
Intervention:   Diagnostic Test: Multiomic analyses of blood and surgical specimens
Sponsors:   University of Cagliari;   Prof. Pietro Giorgio Calò;   Dott. Gian Luigi Canu
Not yet recruiting

Pneumococcal Carriage and Serotype Distribution in Children With Otitis Media in Malaysia.

Conditions:   Streptococcus Pneumonia;   Otitis Media
Intervention:  
Sponsors:   International Medical University;   International Islamic University Malaysia;   Universiti Putra Malaysia;   University of Southampton;   Merck Sharp & Dohme LLC;   Hospital Serdang
Not yet recruiting

Precise Therapy for Refractory HER2 Positive Advanced Breast Cancer

Condition:   HER2+ Breast Cancer
Interventions:   Drug: Trastuzumab;   Drug: Pertuzumab;   Drug: Nab paclitaxel;   Drug: Pyrotinib;   Drug: Capecitabine;   Drug: T-DM1;   Drug: Everolimus;   Drug: CDK4/6 inhibitor;   Drug: AI;   Drug: Anti-PD-1 monoclonal antibody
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University
Recruiting

The Analysis of Gene Variants Related to POCD in Elderly Patients

Condition:   Cognitive Dysfunction
Intervention:   Procedure: Urologic Surgery
Sponsor:   Istanbul University
Not yet recruiting

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