Precision Health Clinical Trials

Genetic, Brain Structure, and Environmental Effects on ADHD

Condition:   Attention Deficit Disorder With Hyperactivity
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Recruiting

Adverse Childhood Experiences in Substance-related Disorders

Conditions:   Alcohol Use Disorder;   Trauma, Psychological
Intervention:   Other: No intervention
Sponsors:   Central Institute of Mental Health, Mannheim;   German Research Foundation
Not yet recruiting

Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies

Conditions:   Breast Cancer;   Ovarian Cancer;   Uterine Cancer
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

TS Overexpression in SCLC: Mechanism and Therapeutic Targeting

Condition:   Small Cell Lung Cancer
Intervention:  
Sponsors:   Wake Forest University Health Sciences;   National Cancer Institute (NCI)
Recruiting

MSI in Circulatory DNA of Endometrial Cancer

Conditions:   Microsatellite Instability;   Lynch Syndrome;   Endometrial Cancer;   Circulating Tumor Cell
Intervention:  
Sponsor:   Lei Li
Recruiting

A Study of the Role of Circulating Tumor DNA in Predicting the Likelihood of Organ Preservation After Clinical Complete Response to Neoadjuvant Therapy for Rectal Cancer

Condition:   Gastrointestinal Malignancies
Intervention:   Other: The Functional Assessment of Cancer Therapy- Colorectal
Sponsors:   Massachusetts General Hospital;   Clinical Genomics
Not yet recruiting

Genomic Investigation of Unusual Responders

Conditions:   Cancer;   Breast Cancer;   Non-small Cell Lung Cancer;   Colorectal Cancer;   Genitourinary Cancer;   Gynecological Cancer;   Upper Aerodigestive Tract Cancer;   Pancreatobiliary Gastrointestinal Cancer;   Melanoma (Skin);   Rare Cancer;   Carcinoma of Unknown Primary
Intervention:  
Sponsor:   University Health Network, Toronto
Recruiting

Deciphering Antitumour Response and Resistance With INtratumour Heterogeneity

Condition:   Non-small Cell Lung Cancer
Interventions:   Drug: MPDL3280A;   Drug: Vemurafenib;   Drug: Alectinib;   Drug: Trastuzumab emtansine
Sponsors:   University College, London;   Hoffmann-La Roche
Recruiting

Targeted Next Generation Sequencing for the Efficacy of Trastuzumab Neoadjuvant Chemotherapy in Breast Cancer

Conditions:   Observational;   Prospective
Intervention:   Drug: Trastuzumab+TP
Sponsor:   Hebei Medical University Fourth Hospital
Not yet recruiting

Mitochondrial Genetics of Presbycusis

Conditions:   Presbycusis;   Age Related Hearing Loss
Intervention:  
Sponsor:   University Hospital, Angers
Not yet recruiting

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