Precision Health Clinical Trials
A Baseline Study in Support of Clinical Evaluation of an Oral Shigella Vaccine Development in Africa
Conditions: Diarrhea; Diarrhea Infectious
Intervention: Other: no intervention
Sponsors: Centre for Infectious Disease Research in Zambia; European Vaccine Initiative; Groupe de Recherche Action en Sante
Not yet recruiting
Intervention: Other: no intervention
Sponsors: Centre for Infectious Disease Research in Zambia; European Vaccine Initiative; Groupe de Recherche Action en Sante
Not yet recruiting
For more information, visit the Study URL.
Genes and Environment in Multiple Sclerosis
Condition: Multiple Sclerosis
Intervention:
Sponsors: Columbia University; University of Pittsburgh; Brigham and Women's Hospital; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting
Intervention:
Sponsors: Columbia University; University of Pittsburgh; Brigham and Women's Hospital; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting
For more information, visit the Study URL.
PROMOTE: Identifying Predictive Markers of Response for Prostate Cancer
Condition: Prostate Cancer
Interventions: Other: Systemic therapy; Device: StrataNGS
Sponsors: University of California, San Francisco; Prostate Cancer Foundation; Strata Oncology
Recruiting
Interventions: Other: Systemic therapy; Device: StrataNGS
Sponsors: University of California, San Francisco; Prostate Cancer Foundation; Strata Oncology
Recruiting
For more information, visit the Study URL.
GEN2 Directed Cancer Immunotherapy Trial
Conditions: Hepatocellular Carcinoma; Metastatic Cancer
Intervention: Drug: GEN2 (HSV-Thymidine Kinase-m2 and hGM-CSF Genes)
Sponsor: GenVivo, Inc.
Recruiting
Intervention: Drug: GEN2 (HSV-Thymidine Kinase-m2 and hGM-CSF Genes)
Sponsor: GenVivo, Inc.
Recruiting
For more information, visit the Study URL.
Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial
Conditions: Ectomesenchymoma; Recurrent Adrenal Gland Pheochromocytoma; Recurrent Ependymoma; Recurrent Ewing Sarcoma; Recurrent Hepatoblastoma; Recurrent Langerhans Cell Histiocytosis; Recurrent Malignant Germ Cell Tumor; Recurrent Malignant Glioma; Recurrent Medulloblastoma; Recurrent Melanoma; Recurrent Neuroblastoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Osteosarcoma; Recurrent Peripheral Primitive Neuroectodermal Tumor; Recurrent Rhabdoid Tumor; Recurrent Rhabdoid Tumor of the Kidney; Recurrent Rhabdomyosarcoma; Recurrent Soft Tissue Sarcoma; Recurrent Thyroid Gland Carcinoma; Recurrent WHO Grade II Glioma; Refractory Adrenal Gland Pheochromocytoma; Refractory Ependymoma; Refractory Ewing Sarcoma; Refractory Hepatoblastoma; Refractory Langerhans Cell Histiocytosis; Refractory Malignant Germ Cell Tumor; Refractory Malignant Glioma; Refractory Medulloblastoma; Refractory Melanoma; Refractory Neuroblastoma; Refractory Non-Hodgkin Lymphoma; Refractory Osteosarcoma; Refractory Peripheral Primitive Neuroectodermal Tumor; Refractory Rhabdoid Tumor; Refractory Rhabdoid Tumor of the Kidney; Refractory Rhabdomyosarcoma; Refractory Soft Tissue Sarcoma; Refractory Thyroid Gland Carcinoma; Refractory WHO Grade II Glioma; Wilms Tumor
Intervention: Drug: Tipifarnib
Sponsor: National Cancer Institute (NCI)
Not yet recruiting
Intervention: Drug: Tipifarnib
Sponsor: National Cancer Institute (NCI)
Not yet recruiting
For more information, visit the Study URL.
PDAC Peripheral and Portal Vein Sampling
Condition: Pancreatic Adenocarcinoma
Intervention: Diagnostic Test: Portal vein sampling
Sponsors: The Christie NHS Foundation Trust; Manchester University NHS Foundation Trust
Recruiting
Intervention: Diagnostic Test: Portal vein sampling
Sponsors: The Christie NHS Foundation Trust; Manchester University NHS Foundation Trust
Recruiting
For more information, visit the Study URL.
Predicted Biomarkers of CDK4/6 Inhibitors (Palbociclib) in ER-positive Metastasis Breast Cancer
Condition: Breast Cancer
Intervention: Drug: Palbociclib
Sponsors: Chinese Academy of Medical Sciences; OrigiMed
Recruiting
Intervention: Drug: Palbociclib
Sponsors: Chinese Academy of Medical Sciences; OrigiMed
Recruiting
For more information, visit the Study URL.
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity
Conditions: Breast Cancer; Lung Cancer; Gastrointestinal Cancer; Genitourinary Cancer; Gynecologic Cancer; Sarcoma; Unknown Primary Tumors; Head and Neck Cancer; Skin Cancer
Intervention: Drug: Atezolizumab
Sponsors: British Columbia Cancer Agency; Hoffmann-La Roche
Not yet recruiting
Intervention: Drug: Atezolizumab
Sponsors: British Columbia Cancer Agency; Hoffmann-La Roche
Not yet recruiting
For more information, visit the Study URL.
Tessa Jowell BRAIN MATRIX - Platform Study
Condition: Glioma
Intervention: Other: Matched Tumour and Blood Sample
Sponsors: University of Birmingham; The Brain Tumour Charity; University of Oxford; The University of Edinburgh
Not yet recruiting
Intervention: Other: Matched Tumour and Blood Sample
Sponsors: University of Birmingham; The Brain Tumour Charity; University of Oxford; The University of Edinburgh
Not yet recruiting
For more information, visit the Study URL.
An Integrative Genomic Approach to Solve tHe Puzzle of sevERe earLy-Onset COPD
Conditions: COPD; Chronic Obstructive Pulmonary Disease; Severe Early-Onset COPD; SEO-COPD
Intervention:
Sponsor: University Medical Center Groningen
Recruiting
Intervention:
Sponsor: University Medical Center Groningen
Recruiting
For more information, visit the Study URL.