Precision Health Clinical Trials

An Integrative Genomic Approach to Solve tHe Puzzle of sevERe earLy-Onset COPD

Conditions:   COPD;   Chronic Obstructive Pulmonary Disease;   Severe Early-Onset COPD;   SEO-COPD
Intervention:  
Sponsor:   University Medical Center Groningen
Recruiting

Genetics and Genomics of Aspirin Exacerbated Respiratory Disease (AERD)

Conditions:   Aspirin Exacerbated Respiratory Disease;   Aspirin-Sensitive Asthma;   Nasal Polyps
Intervention:  
Sponsors:   National Jewish Health;   The Scripps Research Institute
Recruiting

IBI310 in Combination With Sintilimab in Patients With DNA Mismatch Repair Deficient(dMMR)/Microsatellite Instability High (MSI-H)Locally-advanced or Metastatic Colorectal Cancer

Condition:   Colorectal Cancer
Interventions:   Biological: IBI310 (anti-CTLA-4 antibody);   Biological: Sintilimab(anti-PD-1 antibody)
Sponsor:   Innovent Biologics (Suzhou) Co. Ltd.
Not yet recruiting

DOvEEgene Fleur: New Uterine Sampling Tool

Condition:   Women With Suspected or Confirmed Gynecological Disease
Intervention:   Device: DOvEEgene Fleur Sampling
Sponsors:   McGill University;   McGill University Health Centre/Research Institute of the McGill University Health Centre;   GSE Biomedical
Not yet recruiting

Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas

Condition:   Colonic Neoplasms
Intervention:  
Sponsors:   University of Michigan Rogel Cancer Center;   Early Detection Research Network;   Clinical Genomics Pathology;   VolitionRx;   Department of Health and Human Services;   Great Lakes New England Clinical Validation Center;   National Cancer Institute (NCI)
Recruiting

Integrating Pediatric Pharmacogenomic Testing Into the Canadian Health Care System

Condition:   Adverse Drug Reaction (ADR)
Intervention:  
Sponsors:   University of British Columbia;   Genome British Columbia;   Genome Canada;   Dynacare Laboratories, Inc.
Recruiting

Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery

Conditions:   Colon Adenocarcinoma;   Stage IIA Colon Cancer AJCC v8
Interventions:   Drug: Capecitabine;   Drug: Fluorouracil;   Drug: Leucovorin;   Drug: Leucovorin Calcium;   Drug: Oxaliplatin;   Other: Patient Observation
Sponsors:   NRG Oncology;   National Cancer Institute (NCI)
Recruiting

Immune Resistance Interrogation Study

Conditions:   Cancer;   Solid Tumor;   Metastatic Cancer;   Immune Resistance
Intervention:  
Sponsor:   University Health Network, Toronto
Not yet recruiting

CINSARC Genomic Signature as Predictor of Resectability of Ovarian Adenocarcinoma

Condition:   Ovarian Adenocarcinoma
Intervention:   Other: CINSARC signature
Sponsor:   Institut Claudius Regaud
Recruiting

Evaluation ctDNA in Patients of Non-Small-Cell Lung Cancer Following Resection

Condition:   Non-Small Cell Lung Cancer
Intervention:   Diagnostic Test: Perioperative ctDNA Dynamic Monitoring
Sponsors:   Sun Yat-sen University;   Hangzhou Repugene Technology Co., Ltd.
Recruiting

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