Precision Health Clinical Trials

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Conditions:   Locally Advanced Leiomyosarcoma;   Metastatic Leiomyosarcoma;   Stage III Uterine Corpus Leiomyosarcoma AJCC v8;   Stage IV Uterine Corpus Leiomyosarcoma AJCC v8;   Unresectable Leiomyosarcoma;   Uterine Corpus Leiomyosarcoma
Interventions:   Drug: Olaparib;   Drug: Pazopanib;   Drug: Temozolomide;   Drug: Trabectedin
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

For more information, visit the Study URL.

Establishment of Molecular Classification Models for Early Diagnosis of Digestive System Cancers

Conditions:   Esophageal Cancer;   Gastric (Stomach) Cancer;   Colorectal Cancer;   Hepatocellular Carcinoma
Intervention:  
Sponsors:   Singlera Genomics Inc.;   Fudan University;   Shanghai Public Health Clinical Center;   Xuhui Central Hospital, Shanghai;   Shanghai Zhongshan Hospital
Recruiting

For more information, visit the Study URL.

Clinical Trial Multi-analyte Blood Test

Condition:   Liver Cirrhosis
Intervention:   Diagnostic Test: Multi-analyte blood Test
Sponsor:   Helio Genomics
Recruiting

For more information, visit the Study URL.

Multi-analyte Blood Test Clinical Trial

Conditions:   Liver Cirrhosis;   Liver Cancer;   HCC;   Hepatocellular Carcinoma
Intervention:   Diagnostic Test: Multi-analyte Blood Test
Sponsor:   Helio Genomics
Not yet recruiting

For more information, visit the Study URL.

Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

Conditions:   Cancer;   Liver Cirrhosis;   Chronic Hepatitis;   Hepatitis B;   Hepatitis C;   Diabetes;   COPD
Intervention:   Diagnostic Test: Multi-analyte Blood Test
Sponsor:   Helio Genomics
Recruiting

For more information, visit the Study URL.

Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in MDS

Conditions:   Whole Genome Sequencing;   Myelodysplastic Syndromes
Intervention:   Device: ChromoSeq
Sponsor:   Washington University School of Medicine
Not yet recruiting

For more information, visit the Study URL.

Assessment the Cancer Risk of Indeterminate Thyroid Nodules Through Integration of Clinical, Ultrasonographic and Multiomic Features

Conditions:   Thyroid Nodule;   Thyroid Cancer
Intervention:   Diagnostic Test: Multiomic analyses of blood and surgical specimens
Sponsors:   University of Cagliari;   Prof. Pietro Giorgio Calò;   Dott. Gian Luigi Canu
Not yet recruiting

For more information, visit the Study URL.

Pneumococcal Carriage and Serotype Distribution in Children With Otitis Media in Malaysia.

Conditions:   Streptococcus Pneumonia;   Otitis Media
Intervention:  
Sponsors:   International Medical University;   International Islamic University Malaysia;   Universiti Putra Malaysia;   University of Southampton;   Merck Sharp & Dohme LLC;   Hospital Serdang
Not yet recruiting

For more information, visit the Study URL.

Precise Therapy for Refractory HER2 Positive Advanced Breast Cancer

Condition:   HER2+ Breast Cancer
Interventions:   Drug: Trastuzumab;   Drug: Pertuzumab;   Drug: Nab paclitaxel;   Drug: Pyrotinib;   Drug: Capecitabine;   Drug: T-DM1;   Drug: Everolimus;   Drug: CDK4/6 inhibitor;   Drug: AI;   Drug: Anti-PD-1 monoclonal antibody
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University
Recruiting

For more information, visit the Study URL.

The Analysis of Gene Variants Related to POCD in Elderly Patients

Condition:   Cognitive Dysfunction
Intervention:   Procedure: Urologic Surgery
Sponsor:   Istanbul University
Not yet recruiting

For more information, visit the Study URL.

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