Precision Health Clinical Trials

Sepsis in Oncology Patients

Condition:   Sepsis in Cancer Patients
Intervention:   Other: No intervention
Sponsor:   Royal Marsden NHS Foundation Trust
Not yet recruiting

Individualized Treatments in Adults With Relapsed/Refractory Cancers

Conditions:   Refractory Cancer;   Relapsed Cancer
Intervention:   Diagnostic Test: Drug Sensitivity Test (DST)
Sponsor:   Case Comprehensive Cancer Center
Not yet recruiting

MultiOmic characteriZation of Acute Myeloid Leukemia Evolving From myelopRoliferative Neoplasm to Identify New Targeted Therapeutic Strategies

Conditions:   Myeloproliferative Neoplasm;   Secondary Leukemia
Interventions:   Other: Multiomic characterization;   Other: In vitro drug screening
Sponsors:   University Hospital, Angers;   University Hospital, Brest;   Institut Paoli-Calmettes;   Saint-Louis Hospital, Paris, France;   Gustave Roussy, Cancer Campus, Grand Paris
Not yet recruiting

Mutational Oncology in Clinical Practice

Conditions:   Genome Instability;   Genetic Predisposition to Disease;   Gene Rearrangement
Intervention:   Genetic: Diagnostic Test
Sponsor:   Fondazione Policlinico Universitario Agostino Gemelli IRCCS

INTERogating Cancer for Etiology, Prevention and Therapy Navigation

Conditions:   Cancer;   Cancer Gene Mutation;   PAN Gene Mutation
Intervention:   Genetic: Pan-genomic Testing
Sponsor:   Mayo Clinic
Not yet recruiting

I/II Phase Study Evaluating M1774 in Combination With Fulvestrant in HR+ and HER2- Advanced Breast Cancers

Condition:   Breast Cancer
Interventions:   Drug: M1774;   Drug: Fulvestrant injection
Sponsors:   Institut Paoli-Calmettes;   Merck Sharp & Dohme LLC;   National Cancer Institute, France
Not yet recruiting

Metagenomic NGS for Diagnosis of Pneumonia

Conditions:   Pneumonia;   Diagnosis
Interventions:   Diagnostic Test: Metagenomic next-generation sequencing;   Diagnostic Test: Standard work-up for pneumonia
Sponsors:   National Taiwan University Hospital;   National Taiwan University Hospital Hsin-Chu Branch;   Far Eastern Memorial Hospital
Not yet recruiting

Genomic Approaches to Dissect Human Host-pathogen Interactions in the Amazonian Rainforest

Condition:   Host-Pathogen Interactions
Sponsors:   Universidad Peruana Cayetano Heredia;   Institut Pasteur
Not yet recruiting

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

Condition:   Genetic Disease
Sponsor:   National Human Genome Research Institute (NHGRI)

Impact of Reducing Colistin Use on Colistin Resistance in Humans and Poultry in Indonesia

Conditions:   Colonization, Asymptomatic;   Colistin;   Mcr-1;   Antimicrobial Resistance
Intervention:   Other: screening
Sponsors:   Erasmus Medical Center;   Indonesia University;   Center For Indonesian Veterinary Analytical Studies;   Utrecht University;   Institute of Tropical Medicine;   University of Calgary;   Directorate of Veterinary Public Health, Ministry of Agriculture
Not yet recruiting