Precision Health Clinical Trials

Screening of Susceptibility Genes for APAP Induced Drug Induced LIver Injury in ChiNese Population: a Case-control Study

Conditions:   Acetaminophen;   Drug-Induced Liver Injury;   Pharmacogenetics;   China
Intervention:   Genetic: genetic polymorphism
Sponsors:   The First Affiliated Hospital with Nanjing Medical University;   University of Colorado, Denver;   Beijing Genomics Institute;   Nanjing Medical University
Recruiting

Phenotype and Prognosis of Patients With Breast Cancer and Pathogenic Variants of TP53

Conditions:   Breast Cancer;   TP53 R337H;   Li-Fraumeni Syndrome;   Prognosis Breast Cancer
Intervention:   Other: No intervention in this study
Sponsor:   Instituto do Cancer do Estado de São Paulo
Recruiting

Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy

Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myeloproliferative Syndrome
Intervention:   Genetic: Genomic profiling
Sponsors:   Dana-Farber Cancer Institute;   Charles H. Hood Foundation
Recruiting

HypErsensitiVity PneumonITis: DiseAse Progression Characterization

Condition:   Hypersensitivity Pneumonitis
Intervention:   Other: Disease assessment
Sponsors:   Hospital do Coracao;   Boehringer Ingelheim
Not yet recruiting

The Association Between LPCAT1 Genetic Polymorphism and Stress Biomarkers in Neonatal Respiratory Distress Syndrome

Condition:   Neonatal Respiratory Distress
Intervention:   Diagnostic Test: stress biomarkers
Sponsor:   Assiut University
Recruiting

BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial

Conditions:   Brain Neoplasms;   Liquid Biopsy
Interventions:   Procedure: Magnetic Resonance Guided Focused Ultrasound Tumor Ablation and Liquid Biopsy Acquisition;   Procedure: Magnetic Resonance Guided Focused Ultrasound Thalamotomy
Sponsors:   University Health Network, Toronto;   Canadian Cancer Society (CCS);   Brain Canada
Recruiting

The Oral Microbiome in OSCC

Condition:   Oral Cancer
Interventions:   Dietary Supplement: ProDentis Lozenge;   Other: Placebo Lozenge
Sponsor:   University of Iowa
Not yet recruiting

Retrospective Comparative in Vitro Case-controlled Study of the Liquid Biopsy Test System in Women With Breast Cancer

Condition:   Breast Neoplasm Female
Intervention:   Diagnostic Test: ARNA Breast
Sponsors:   ARNA Genomics US Inc.;   BIOMARKER-RU
Recruiting

Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries

Conditions:   Autologous Stem Cell Transplantation;   Allogeneic Stem Cell Transplantation;   Cellular Therapy;   Marrow Toxic Injury
Intervention:  
Sponsor:   Center for International Blood and Marrow Transplant Research
Recruiting

Genetic Variants Affecting the Clinical Severity of Beta Thalassemia

Condition:   Beta Thalassemia
Intervention:   Diagnostic Test: Hematological Analysis and Genetical Analysis
Sponsors:   Nanfang Hospital of Southern Medical University;   303rd Hospital of the People's Liberation Army;   Liuzhou Municipal Maternity and Child Healthcare Hospital;   Zhuhai Municipal Maternal and Child Healthcare Hospital;   Dong Guan Maternal and Child Health Hospital
Recruiting

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