Precision Health Clinical Trials

Prediction Model for Response to Biologics and Small Molecular Agent for UC

Condition:   Ulcerative Colitis
Intervention:   Drug: Vedolizumab, Ustekinumab, or Tofacitinib
Sponsor:   Asan Medical Center
Not yet recruiting

Molecular Basis of Food Allergy

Conditions:   Food Allergy;   Eosinophilic Esophagitis
Sponsors:   Children's Hospital of Philadelphia;   University of Pennsylvania;   National Institute of Allergy and Infectious Diseases (NIAID)

The FuSion Program: A Prospective and Multicenter Cohort Study of Pan-Cancer Screening in Chinese Population

Condition:   Cancer
Sponsors:   Singlera Genomics Inc.;   Fudan University

Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients >= 18 Years Old With Advanced Stage Rare Cancers, RARE 2 Study

Conditions:   Adrenal Gland Pheochromocytoma;   Hematopoietic and Lymphoid Cell Neoplasm;   Malignant Solid Neoplasm;   Paraganglioma
Interventions:   Drug: Talazoparib;   Drug: Temozolomide
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

Avera/Sema4 Oncology and Analytics Protocol

Conditions:   Cancer;   Cancer Diagnosis;   Early Detection of Cancer;   Breast Cancer;   Lung Cancer;   Colon Cancer;   GI Cancer;   Gynecologic Cancer;   Ovarian Cancer;   Endometrial Cancer;   CNS Cancer;   Hematologic Cancer
Sponsors:   Avera McKennan Hospital & University Health Center;   Sema4

Construction and Biological Study of Blood and Placenta Samples Associated With Gestational Diabetes Mellitus

Condition:   Gestational Diabetes
Intervention:   Diagnostic Test: oral glucose tolerance test
Sponsor:   Second Affiliated Hospital, School of Medicine, Zhejiang University

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

Conditions:   Amyotrophic Lateral Sclerosis;   Movement Disorders;   Degenerative Disorder;   Motor Neuron Disease
Sponsor:   Target ALS Foundation, Inc.

Smurf2 Gene Expression in Urinary Tract Tumors

Condition:   Bladder Neoplasm
Intervention:   Diagnostic Test: immunohistochemistry of tumors samples
Sponsors:   Ziv Hospital;   Azrieli Faculty of medicine, Bar Ilan University, Safed, IL
Not yet recruiting

Longitudinal Assessment of Iron Rims in MS Lesions

Condition:   Multiple Sclerosis
Interventions:   Biological: Blood sample provided;   Diagnostic Test: 7-T MRI scan
Sponsors:   Nottingham University Hospitals NHS Trust;   Johns Hopkins University
Not yet recruiting

Profiling Program of Cancer Patients With Sequential Tumor and Liquid Biopsies (PLANET)

Conditions:   Advanced / Metastic Solid Tumors;   Glioblastoma;   Chronic Leukemia Lymphocytic
Intervention:   Biological: Blood and tumor samples
Sponsor:   Centre Leon Berard