Precision Health Clinical Trials

Screening of Susceptibility Genes for APAP Induced Drug Induced LIver Injury in ChiNese Population: a Case-control Study

Conditions:   Acetaminophen;   Drug-Induced Liver Injury;   Pharmacogenetics;   China
Intervention:   Genetic: genetic polymorphism
Sponsors:   The First Affiliated Hospital with Nanjing Medical University;   University of Colorado, Denver;   Beijing Genomics Institute;   Nanjing Medical University

Phenotype and Prognosis of Patients With Breast Cancer and Pathogenic Variants of TP53

Conditions:   Breast Cancer;   TP53 R337H;   Li-Fraumeni Syndrome;   Prognosis Breast Cancer
Intervention:   Other: No intervention in this study
Sponsor:   Instituto do Cancer do Estado de São Paulo

Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy

Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myeloproliferative Syndrome
Intervention:   Genetic: Genomic profiling
Sponsors:   Dana-Farber Cancer Institute;   Charles H. Hood Foundation

HypErsensitiVity PneumonITis: DiseAse Progression Characterization

Condition:   Hypersensitivity Pneumonitis
Intervention:   Other: Disease assessment
Sponsors:   Hospital do Coracao;   Boehringer Ingelheim
Not yet recruiting

The Association Between LPCAT1 Genetic Polymorphism and Stress Biomarkers in Neonatal Respiratory Distress Syndrome

Condition:   Neonatal Respiratory Distress
Intervention:   Diagnostic Test: stress biomarkers
Sponsor:   Assiut University

BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial

Conditions:   Brain Neoplasms;   Liquid Biopsy
Interventions:   Procedure: Magnetic Resonance Guided Focused Ultrasound Tumor Ablation and Liquid Biopsy Acquisition;   Procedure: Magnetic Resonance Guided Focused Ultrasound Thalamotomy
Sponsors:   University Health Network, Toronto;   Canadian Cancer Society (CCS);   Brain Canada

The Oral Microbiome in OSCC

Condition:   Oral Cancer
Interventions:   Dietary Supplement: ProDentis Lozenge;   Other: Placebo Lozenge
Sponsor:   University of Iowa
Not yet recruiting

Retrospective Comparative in Vitro Case-controlled Study of the Liquid Biopsy Test System in Women With Breast Cancer

Condition:   Breast Neoplasm Female
Intervention:   Diagnostic Test: ARNA Breast
Sponsors:   ARNA Genomics US Inc.;   BIOMARKER-RU

Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries

Conditions:   Autologous Stem Cell Transplantation;   Allogeneic Stem Cell Transplantation;   Cellular Therapy;   Marrow Toxic Injury
Sponsor:   Center for International Blood and Marrow Transplant Research

Genetic Variants Affecting the Clinical Severity of Beta Thalassemia

Condition:   Beta Thalassemia
Intervention:   Diagnostic Test: Hematological Analysis and Genetical Analysis
Sponsors:   Nanfang Hospital of Southern Medical University;   303rd Hospital of the People's Liberation Army;   Liuzhou Municipal Maternity and Child Healthcare Hospital;   Zhuhai Municipal Maternal and Child Healthcare Hospital;   Dong Guan Maternal and Child Health Hospital