Precision Health Clinical Trials

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Conditions:   Schizophrenia;   Cannabis Dependence;   Prodromal for Psychotic Illness;   Family History of Alcoholism;   Healthy Control;   Opioid-use Disorder;   Post Traumatic Stress Disorder
Intervention:   Radiation: [11-C]OMAR
Sponsors:   Yale University;   National Institute on Drug Abuse (NIDA);   National Institute of Mental Health (NIMH)
Recruiting

Intestinal Microbiome Composition in Infants With Biliary Atresia (BA)

Conditions:   Biliary Atresia;   Intrahepatic Cholestases;   Normal Controls
Intervention:  
Sponsors:   Children's Hospital Medical Center, Cincinnati;   Wuhan Union Hospital, China
Not yet recruiting

Clinical, Molecular and Functional Biomarkers for PROgnosis, Pathomechanisms and Treatment Strategies of COVID-19

Condition:   COVID-19 Pneumonia
Intervention:  
Sponsors:   Charite University, Berlin, Germany;   German Federal Ministry of Education and Research;   University of Leipzig;   University of Jena
Recruiting

Screening of Susceptibility Genes for APAP Induced Drug Induced LIver Injury in ChiNese Population: a Case-control Study

Conditions:   Acetaminophen;   Drug-Induced Liver Injury;   Pharmacogenetics;   China
Intervention:   Genetic: genetic polymorphism
Sponsors:   The First Affiliated Hospital with Nanjing Medical University;   University of Colorado, Denver;   Beijing Genomics Institute;   Nanjing Medical University
Recruiting

Phenotype and Prognosis of Patients With Breast Cancer and Pathogenic Variants of TP53

Conditions:   Breast Cancer;   TP53 R337H;   Li-Fraumeni Syndrome;   Prognosis Breast Cancer
Intervention:   Other: No intervention in this study
Sponsor:   Instituto do Cancer do Estado de São Paulo
Recruiting

Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy

Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myeloproliferative Syndrome
Intervention:   Genetic: Genomic profiling
Sponsors:   Dana-Farber Cancer Institute;   Charles H. Hood Foundation
Recruiting

HypErsensitiVity PneumonITis: DiseAse Progression Characterization

Condition:   Hypersensitivity Pneumonitis
Intervention:   Other: Disease assessment
Sponsors:   Hospital do Coracao;   Boehringer Ingelheim
Not yet recruiting

The Association Between LPCAT1 Genetic Polymorphism and Stress Biomarkers in Neonatal Respiratory Distress Syndrome

Condition:   Neonatal Respiratory Distress
Intervention:   Diagnostic Test: stress biomarkers
Sponsor:   Assiut University
Recruiting

BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial

Conditions:   Brain Neoplasms;   Liquid Biopsy
Interventions:   Procedure: Magnetic Resonance Guided Focused Ultrasound Tumor Ablation and Liquid Biopsy Acquisition;   Procedure: Magnetic Resonance Guided Focused Ultrasound Thalamotomy
Sponsors:   University Health Network, Toronto;   Canadian Cancer Society (CCS);   Brain Canada
Recruiting

The Oral Microbiome in OSCC

Condition:   Oral Cancer
Interventions:   Dietary Supplement: ProDentis Lozenge;   Other: Placebo Lozenge
Sponsor:   University of Iowa
Recruiting

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