Precision Health Clinical Trials

Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal

Conditions:   Hematopoietic and Lymphoid System Neoplasm;   Metastatic Malignant Solid Neoplasm
Interventions:   Procedure: Biopsy Specimen;   Procedure: Biospecimen Collection;   Other: Medical Chart Review
Sponsor:   Mayo Clinic
Recruiting

Detection of Tumor DNA Through Cervical Smear and Liquid Biopsy in Endometrial Cancer Patients and Evaluation of Prognostic and Predictive Values of Tumor DNA Assay

Condition:   Endometrial Cancer
Intervention:  
Sponsor:   Yonsei University
Recruiting

Familial and Functional Study of Genetic Variants Identified in People With Schizophrenia, Bipolar Disorder, Autism Spectrum Disorder or Resistant Depression

Condition:   Psychiatric Disorder
Intervention:   Genetic: study of the transmission of genetic variants
Sponsor:   Fondation FondaMental
Not yet recruiting

'Lung Health Check' Biomarker Study

Conditions:   Lung Cancer;   Cancer
Intervention:   Diagnostic Test: Blood Specimen
Sponsors:   Royal Marsden NHS Foundation Trust;   Royal Brompton & Harefield NHS Foundation Trust;   Imperial College London;   Royal Marsden Partners Cancer Alliance
Recruiting

Functional Precision Oncology to Predict, Prevent, and Treat Early Metastatic Recurrence of TNBC

Condition:   Breast Cancer Recurrent
Intervention:   Other: Functional Precision Oncology
Sponsors:   University of Utah;   United States Department of Defense
Not yet recruiting

THIO Sequenced With Cemiplimab in Advanced NSCLC

Condition:   Carcinoma, Non-Small-Cell Lung
Interventions:   Drug: 6-Thio-2'-Deoxyguanosine;   Drug: Cemiplimab
Sponsor:   Maia Biotechnology
Recruiting

Antibiotyping and Prevalence of Virulent Genotypes Among Helicobacter Pylori and Their Impact on Response to Therapy

Condition:   H Pylori Infection
Interventions:   Genetic: detection of vacuolating cytotoxin A (Vac A) and cytotoxin-associated gene A (Cag A) virulent H.Pylori genotypes by polymerase chain reaction amplification(PCR) in gastric biopsies :;   Diagnostic Test: Culture and sensitivity of endoscopic gastric biopsies:;   Other: Histopathological examination endoscopic gastric biopsies:;   Procedure: Upper endoscopy;   Drug: empirical H.pylori regimens;   Diagnostic Test: H.Pylori Ag in stool
Sponsor:   Assiut University
Not yet recruiting

BioMEL- Diagnostic and Prognostic Factors in Melanoma.

Conditions:   Melanoma;   Melanoma in Situ;   Dysplastic Nevi;   Mole (Dermatology);   Image;   Mutation
Intervention:   Diagnostic Test: Imaging
Sponsor:   Region Skane
Recruiting

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Conditions:   Locally Advanced Leiomyosarcoma;   Locally Advanced Uterine Corpus Leiomyosarcoma;   Metastatic Leiomyosarcoma;   Metastatic Uterine Corpus Leiomyosarcoma;   Stage III Uterine Corpus Leiomyosarcoma AJCC v8;   Stage IV Uterine Corpus Leiomyosarcoma AJCC v8;   Unresectable Leiomyosarcoma;   Unresectable Uterine Corpus Leiomyosarcoma;   Uterine Corpus Leiomyosarcoma
Interventions:   Drug: Olaparib;   Drug: Pazopanib;   Drug: Temozolomide;   Drug: Trabectedin
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

Establishment of Molecular Classification Models for Early Diagnosis of Digestive System Cancers

Conditions:   Esophageal Cancer;   Gastric (Stomach) Cancer;   Colorectal Cancer;   Hepatocellular Carcinoma
Intervention:  
Sponsors:   Singlera Genomics Inc.;   Fudan University;   Shanghai Public Health Clinical Center;   Xuhui Central Hospital, Shanghai;   Shanghai Zhongshan Hospital
Recruiting

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