Precision Health Clinical Trials

The Association Between LPCAT1 Genetic Polymorphism and Stress Biomarkers in Neonatal Respiratory Distress Syndrome

Condition:   Neonatal Respiratory Distress
Intervention:   Diagnostic Test: stress biomarkers
Sponsor:   Assiut University
Recruiting

BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial

Conditions:   Brain Neoplasms;   Liquid Biopsy
Interventions:   Procedure: Magnetic Resonance Guided Focused Ultrasound Tumor Ablation and Liquid Biopsy Acquisition;   Procedure: Magnetic Resonance Guided Focused Ultrasound Thalamotomy
Sponsors:   University Health Network, Toronto;   Canadian Cancer Society (CCS);   Brain Canada
Recruiting

The Oral Microbiome in OSCC

Condition:   Oral Cancer
Interventions:   Dietary Supplement: ProDentis Lozenge;   Other: Placebo Lozenge
Sponsor:   University of Iowa
Not yet recruiting

Retrospective Comparative in Vitro Case-controlled Study of the Liquid Biopsy Test System in Women With Breast Cancer

Condition:   Breast Neoplasm Female
Intervention:   Diagnostic Test: ARNA Breast
Sponsors:   ARNA Genomics US Inc.;   BIOMARKER-RU
Recruiting

Genetic Variants Affecting the Clinical Severity of Beta Thalassemia

Condition:   Beta Thalassemia
Intervention:   Diagnostic Test: Hematological Analysis and Genetical Analysis
Sponsors:   Nanfang Hospital of Southern Medical University;   303rd Hospital of the People's Liberation Army;   Liuzhou Municipal Maternity and Child Healthcare Hospital;   Zhuhai Municipal Maternal and Child Healthcare Hospital;   Dong Guan Maternal and Child Health Hospital
Recruiting

Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries

Conditions:   Autologous Stem Cell Transplantation;   Allogeneic Stem Cell Transplantation;   Cellular Therapy;   Marrow Toxic Injury
Intervention:  
Sponsor:   Center for International Blood and Marrow Transplant Research
Recruiting

Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Conditions:   Acute Leukemia of Ambiguous Lineage in Relapse;   Acute Myeloid Leukemia, in Relapse;   Refractory Acute Leukemia of Ambiguous Lineage;   Refractory Acute Myeloid Leukemia
Interventions:   Drug: Venetoclax;   Drug: Selinexor;   Drug: Cytarabine;   Drug: Fludarabine;   Biological: Filgrastim;   Drug: Methotrexate;   Drug: methotrexate/hydrocortisone/cytarabine
Sponsors:   St. Jude Children's Research Hospital;   Karyopharm Therapeutics Inc;   AbbVie;   Gateway for Cancer Research
Recruiting

In Vitro Study of the Liquid Biopsy Test System of the Diagnostic Value, in Women With Various Forms of Breast Cancer

Condition:   Breast Neoplasms
Intervention:   Diagnostic Test: ARNA Breast
Sponsors:   ARNA Genomics US Inc.;   BIOMARKER-RU
Not yet recruiting

From Genetics to Transcriptomics to Unravel the Mechanisms Behind a Poor Outcome in Multiple Sclerosis

Condition:   Multiple Sclerosis
Intervention:   Other: Biological sample collection
Sponsor:   Nantes University Hospital
Recruiting

Genomic Analysis of Families With a History of Discordant Cancers

Condition:   Discordant Cancers
Interventions:   Genetic: WES via Illumina NextSeq 550 sequencing system;   Diagnostic Test: Blood Draw;   Diagnostic Test: Skin biopsy;   Diagnostic Test: Saliva Sample
Sponsor:   Case Comprehensive Cancer Center
Not yet recruiting

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