Precision Health Clinical Trials

Development of Free DNA Multi-target Methylated PCR for Auxiliary Diagnosis of Gastric Cancer

Condition:   Stomach Cancer
Intervention:   Other: No intervention
Sponsors:   Singlera Genomics Inc.;   Fudan University
Recruiting

For more information, visit the Study URL.

The Aim is to Identify Recurrent Genomic Mutations and/or Predisposing Polymorphisms in Patients With Sporadic Cases of Multiple Myeloma

Condition:   Multiple Myeloma
Intervention:   Genetic: DNA sequencing
Sponsor:   Hospices Civils de Lyon
Not yet recruiting

For more information, visit the Study URL.

Genetic Aspects of Vaginal Aging

Condition:   Genitourinary Agents
Intervention:  
Sponsors:   Żelazna Medical Centre, LLC;   Laboratory of Genetics and Human Genomics, University of Gdańsk
Recruiting

For more information, visit the Study URL.

Patient Derived Preclinical Models

Condition:   Cancer
Interventions:   Procedure: Tissue Collection;   Diagnostic Test: Blood Collection;   Diagnostic Test: Buccal Swab
Sponsor:   Mayo Clinic
Recruiting

For more information, visit the Study URL.

An Observational Cohort Study to Obese Patients With Weight Cycling

Conditions:   Weight Cycling;   Obesity
Intervention:  
Sponsor:   Peking Union Medical College Hospital
Recruiting

For more information, visit the Study URL.

Chromosomal Instability in Ovarian Cancer

Conditions:   Epithelial Ovarian Cancer;   High-grade Serous Ovarian Carcinoma;   Chromosomal Instability;   Somatic Copy Number Distortion;   Survival Outcomes;   Minimal Residual Lesions;   Progression-free Survival;   Overall Survival
Intervention:   Diagnostic Test: Testing for chromosomal instability (CIN)
Sponsor:   Lei Li
Recruiting

For more information, visit the Study URL.

Translational Immunodiagnostics in Stroke (TrImS)

Conditions:   Acute Ischemic Stroke;   Haemorrhagic Stroke;   Transient Ischemic Attacks;   Cardioembolic Stroke;   Large-Artery Atherosclerosis (Embolus/Thrombosis);   Small Vessel Disease;   Stroke of Other Determined Etiology;   Stroke of Undetermined Etiology;   Atrial Fibrillation;   Stroke of Anterior Cerebral Artery;   Stroke of Middle Cerebral Artery;   Stroke of Basilar Artery
Intervention:   Diagnostic Test: Biomarker blood draw and saliva collection
Sponsor:   The University of Hong Kong
Recruiting

For more information, visit the Study URL.

Omics-based Predictors of NAFLD/Potential NASH

Conditions:   Non-Alcoholic Fatty Liver Disease;   Non Alcoholic Steatohepatitis
Interventions:   Diagnostic Test: Genomics (DNA Extraction);   Diagnostic Test: Epi-genomics;   Diagnostic Test: Proteomics (Glycoproteomics);   Diagnostic Test: Salivary Metabolomics;   Behavioral: Individualized counselling for behavioural modification
Sponsor:   National Research Centre, Egypt
Not yet recruiting

For more information, visit the Study URL.

Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort

Conditions:   Developmental Disability;   Intellectual Disability;   Autism Spectrum Disorder;   Congenital Anomaly;   Fragile X Syndrome;   Facioscapulohumeral Muscular Dystrophy 1
Intervention:   Other: Standard of care genetic testing group
Sponsors:   Bionano Genomics;   University of Rochester;   Columbia University;   Greenwood Genetic Center;   Praxis Genomics;   Augusta University;   Medical College of Wisconsin;   University of Iowa
Recruiting

For more information, visit the Study URL.

Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities. CHROmosome MAPping and Sequencing (CHROMAPS)

Conditions:   Infertility;   Intellectual Disability;   Malformation
Interventions:   Genetic: Optical Genome Mapping (Bionano®);   Genetic: Longread sequencing (Nanopore®)
Sponsor:   Institut National de la Santé Et de la Recherche Médicale, France
Not yet recruiting

For more information, visit the Study URL.

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