Precision Health Clinical Trials

Identification of Genomic Biomarkers for Rheumatoid Arthritis With Late Onset

Condition:   Rheumatoid Arthritis
Intervention:   Other: Salivary sampling
Sponsor:   Centre Hospitalier Sud Francilien
Not yet recruiting

PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Aarhus

Conditions:   Overweight and Obesity;   Weight Loss;   Pregnancy Related;   Child Nutrition Sciences;   Body Composition
Intervention:   Behavioral: Weight loss intervention
Sponsors:   Ulla Kampmann Opstrup;   Per Ovesen, Professor Dept. of Obsteterics, Aarhus University Hospital;   Jens Meldgaard Bruun, Professor Steno Diabetes Center Aarhus, Aarhus University Hospital;   Sine Knorr, PhD Steno Diabetes Center Aarhus, Aarhus University Hospital
Not yet recruiting

Liquid Biopsy to Enable Diagnostics and Monitoring for Immune-mediated Lymphoproliferative Disorders

Conditions:   Lymphoproliferative Disorders;   Lymphoproliferative Disorder Following Transplantation
Intervention:   Diagnostic Test: Liquid biopsy
Sponsor:   University Hospital, Geneva

Multiomics Approach in Metastatic Clear Renal Cell Carcnoma

Condition:   Metastatic Clear Cell Renal Carcinoma
Interventions:   Radiation: CT scan;   Biological: Plasma collection
Sponsor:   Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Study to Assess the Feasibility in Bile cfDNA of Resectable Biliary Tract Carcinomas

Condition:   This Study Aims to Reveal the Effectiveness, Accuracy, and Feasibility in Bile
Intervention:   Diagnostic Test: Next generation sequencing
Sponsor:   Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

Condition:   Crohn Disease
Intervention:   Biological: infliximab, adalimumab
Sponsors:   Connecticut Children's Medical Center;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Emory University;   Children's Hospital Medical Center, Cincinnati;   University of North Carolina, Chapel Hill

Observational, Prospective, Cohort Study of Mpox Infection in Brazil (NETPOX)

Conditions:   Monkeypox;   MPOX
Interventions:   Diagnostic Test: Viral genomic;   Diagnostic Test: Untargeted Metabolomics
Sponsors:   Hospital Israelita Albert Einstein;   Ministry of Health, Brazil
Not yet recruiting

Self-harm Behaviour Among the Most At-risk Adolescents

Conditions:   Self-harm;   Personality Disorder, Borderline;   Epigenetic Disorder;   Non-Suicidal Self Injury;   Change; Mental;   Difference, Individual
Interventions:   Diagnostic Test: Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3;   Diagnostic Test: Columbia Suicide Severity Rating Scale (CSSRS);   Diagnostic Test: The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT);   Diagnostic Test: Experiences in Close Relationships-Relationship Structures (ECR-RS);   Diagnostic Test: Trauma Symptom Checklist for Children (TSCC);   Diagnostic Test: Personality Assessment Inventory-Adolescent (PAI-A);   Diagnostic Test: Inventory Of Statements About Self-Injury; ISAS;   Diagnostic Test: The Level of Personality Functioning Scale-Brief Form 2.0; LPFSBF 2.0;   Diagnostic Test: Borderline Personality Features Scale, BPFSC-11;   Other: Dynamic Appraisal of Situational Aggression-Youth Version (DASA-YV);   Other: Adolescent Self-Harm Risk Scale; ASHRS;   Diagnostic Test: Lifetime Incidence of Traumatic Events questionnaire (LITE);   Genetic: Genetic methods
Sponsors:   University of Ljubljana, Faculty of Medicine;   University Medical Centre Ljubljana;   University Maribor;   University Psychiatric Clinic Ljubljana

On-treatment Biomarkers in Metastatic Colorectal Cancer for Life

Conditions:   Metastatic Colorectal Cancer;   Chemotherapy Effect;   Peritoneal Metastases;   Liver Metastasis Colon Cancer;   Lung Metastases
Interventions:   Drug: Chemotherapy;   Procedure: Resection of the primary tumor;   Procedure: Resection of tumour metastases;   Procedure: Blood sampling during chemotherapy
Sponsor:   Region Skane

African Cancer Genome: GMD

Conditions:   Breast Cancer;   Prostate Cancer
Intervention:   Other: Standard of Care
Sponsors:   Fox Chase Cancer Center;   University of Miami Sylvester Comprehensive Cancer Center;   Pfizer;   The University of The West Indies, Mona, Jamaica;   Kenya Medical Research Institute;   University of Nairobi, Kenya;   University of Abomey Calavi, Benin;   Innovating Health International, Haiti;   Institut de Recherche en Sciences de la Sante, Burkina Faso;   The University of the West Indies at Cave Hill, Barbados;   The University of The West Indies School of Clinical Medicine and Research, The Bahamas;   Ministry of Health and Social Services, Namibia;   Morgan State University;   University of Alabama, Tuscaloosa