Precision Health Clinical Trials

Biomarker Analysis of HIPEC Combined With PD1/PDL1 Inhibitor for Gastric Cancer With Peritoneal Metastasis

Condition:   Gastric Cancer
Intervention:   Other: Observational
Sponsor:   Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Not yet recruiting

Vitamin D Deficiency With Selected Vitamin D Receptor Gene Polymorphism in Gestational Hypertension

Conditions:   Hypertensive Disorder of Pregnancy;   Vitamin D Deficiency
Intervention:   Diagnostic Test: Blood taking
Sponsors:   Universiti Putra Malaysia;   Ministry of Higher Education Malaysia
Recruiting

Liquid Biopsy in Advanced Oligometastatic NSCLC Receiving Surgery

Conditions:   Non-small Cell Lung Cancer;   Oligometastatic Disease
Intervention:   Genetic: ctDNA testing and whole exome sequencing
Sponsor:   Guangdong Provincial People's Hospital
Recruiting

Molecular Profiling and Dynamic Changes of ctDNA in Unresectable Locally Advanced NSCLC

Conditions:   Lung Cancer;   Stage III Lung Cancer;   Unresectable Lung Carcinoma
Interventions:   Procedure: Sample collection;   Diagnostic Test: Characterization of the tumoral tissue genomic alterations;   Drug: Chemoradiation treatment regimen and maintenance (if amenable);   Diagnostic Test: Genomic and methylation analysis in liquid biopsy
Sponsors:   Parc de Salut Mar;   GUARDANT HEALTH
Recruiting

Chinese Regional Spinal Muscular Atrophy Patient Registration Study

Condition:   Recruitment
Intervention:  
Sponsor:   The Children's Hospital of Zhejiang University School of Medicine
Recruiting

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Conditions:   Locally Advanced Leiomyosarcoma;   Metastatic Leiomyosarcoma;   Stage III Uterine Corpus Leiomyosarcoma AJCC v8;   Stage IV Uterine Corpus Leiomyosarcoma AJCC v8;   Unresectable Leiomyosarcoma;   Uterine Corpus Leiomyosarcoma
Interventions:   Drug: Olaparib;   Drug: Temozolomide;   Drug: Trabectedin;   Drug: Pazopanib
Sponsors:   Alliance for Clinical Trials in Oncology;   National Cancer Institute (NCI)
Recruiting

Pilot Study to Detect Monkey Pox Virus in Sperm: POXSPERM

Condition:   Monkeypox
Intervention:   Biological: Samples
Sponsor:   University Hospital, Toulouse
Not yet recruiting

ctDNA and Organ Preservation/Pathologic CR in Rectal Cancer

Conditions:   Rectal Cancer;   Non Metastatic Rectal Cancer
Intervention:   Other: ctDNA
Sponsors:   Massachusetts General Hospital;   C2i Genomics;   Spier Family Foundation
Not yet recruiting

Establishment of a Clinical Diagnostic Model GAMAD for Early-stage HCC Based on Circulating Tumor DNA Methylation

Condition:   Hepatocellular Carcinoma
Intervention:   Diagnostic Test: GAMAD
Sponsors:   Singlera Genomics Inc.;   The First Hospital of Jilin University
Not yet recruiting

Screening for Cystic Fibrosis and Cystic Fibrosis Related Disorders in Chinese Adults With Bronchiectasis

Condition:   Cystic Fibrosis, Pulmonary
Intervention:   Diagnostic Test: Sweat Test
Sponsor:   Shanghai Pulmonary Hospital, Shanghai, China
Recruiting

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