Precision Health Clinical Trials

Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

Conditions:   Cancer;   Liver Cirrhosis;   Chronic Hepatitis;   Hepatitis B;   Hepatitis C;   Diabetes;   COPD
Intervention:   Diagnostic Test: Multi-analyte Blood Test
Sponsor:   Helio Genomics

Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in MDS

Conditions:   Whole Genome Sequencing;   Myelodysplastic Syndromes
Intervention:   Device: ChromoSeq
Sponsor:   Washington University School of Medicine

Assessment the Cancer Risk of Indeterminate Thyroid Nodules Through Integration of Clinical, Ultrasonographic and Multiomic Features

Conditions:   Thyroid Nodule;   Thyroid Cancer
Intervention:   Diagnostic Test: Multiomic analyses of blood and surgical specimens
Sponsors:   University of Cagliari;   Prof. Pietro Giorgio Calò;   Dott. Gian Luigi Canu
Not yet recruiting

Pneumococcal Carriage and Serotype Distribution in Children With Otitis Media in Malaysia.

Conditions:   Streptococcus Pneumonia;   Otitis Media
Sponsors:   International Medical University;   International Islamic University Malaysia;   Universiti Putra Malaysia;   University of Southampton;   Merck Sharp & Dohme LLC;   Hospital Serdang
Not yet recruiting

Precise Therapy for Refractory HER2 Positive Advanced Breast Cancer

Condition:   HER2+ Breast Cancer
Interventions:   Drug: Trastuzumab;   Drug: Pertuzumab;   Drug: Nab paclitaxel;   Drug: Pyrotinib;   Drug: Capecitabine;   Drug: T-DM1;   Drug: Everolimus;   Drug: CDK4/6 inhibitor;   Drug: AI;   Drug: Anti-PD-1 monoclonal antibody
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University

The Analysis of Gene Variants Related to POCD in Elderly Patients

Condition:   Cognitive Dysfunction
Intervention:   Procedure: Urologic Surgery
Sponsor:   Istanbul University
Not yet recruiting

Prediction of Postoperative Treatment Efficacy and Recurrence Risk of High-risk GIST Based on Minimal Residual Disease Detected by Liquid Biopsy

Conditions:   Gastrointestinal Stromal Tumors;   Minimal Residual Disease
Intervention:   Diagnostic Test: liquid biopsy
Sponsor:   Peking University People's Hospital

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

Conditions:   Breast Cancer;   Colorectal Cancer;   Pancreas Cancer;   Kidney Cancer;   Prostate Cancer;   Ovary Cancer;   Head and Neck Cancer;   Leukemia;   Lymphoma;   Lung Cancer;   Melanoma;   Solid Tumor
Sponsors:   University Health Network, Toronto;   Princess Margaret Hospital, Canada;   Ontario Institute for Cancer Research;   Terry Fox Research Institute

Diabetic Ketoacidosis From New SGLT2i: Can Genomics Estimate Risk

Conditions:   Diabetes Type 2;   DKA;   Diabetic Ketoacidosis
Intervention:   Genetic: Genomic analysis
Sponsors:   Mount Sinai Hospital, Canada;   Unity Health Toronto;   University Health Network, Toronto;   Sault Area Hospital
Not yet recruiting

FLT3-ITD Gene Mutation and CD135 Expression in Acute Myeloid Leukemia.

Condition:   Acute Myeloid Leukemia
Sponsor:   Assiut University
Not yet recruiting