Precision Health Clinical Trials

Personalized Trial in ctDNA-level-relapse Glioblastoma

Condition:   Glioblastoma
Intervention:   Other: Individualized intervention based on genomic alterations
Sponsor:   Henan Provincial People's Hospital
Not yet recruiting

Implications of Maternal 45,X Mosaicism as a Secondary Genomic Finding Following Cell-Free DNA Sequencing During Pregnancy: A Deep Phenotype Study

Conditions:   Cardiovascular Phenotype;   Metabolic Phenotype;   Hypertensive Disease;   Psychological Phenotype;   Audio
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Not yet recruiting

iPSC Repository of Pediatric Cardiovascular Disease

Conditions:   Congenital Heart Disease;   Heart Diseases
Intervention:   Procedure: Blood draw
Sponsor:   Mingtao Zhao

Circulating Tumor DNA and BRCA Reversion Mutation in Advanced or Recurrent Ovarian Cancer Patients With Germline Mutation.

Condition:   Ovarian Cancer
Sponsor:   Yonsei University

Clinical, Translational and Biomarker-Based Female Genital HPV Induced Dysplasia and Cancer Screening Study Using Cf-HPV-DNA Blood Tests

Conditions:   Cervical Dysplasia, Uterine;   Vaginal Dysplasia;   Vulvar Dysplasia
Sponsor:   University of Mississippi Medical Center
Not yet recruiting

The Role of Circulating Tumour DNA in Head and Neck Cancer

Conditions:   Oropharyngeal Squamous Cell Carcinoma;   Human Papillomavirus (HPV)
Sponsor:   University of Edinburgh

ctDNA Methylation Application in Postoperative Relapse and Adjuvant Chemotherapy Efficacy Evaluation

Condition:   Cancer Colorectal
Intervention:   Diagnostic Test: a multi-locus blood-based assay
Sponsors:   Singlera Genomics Inc.;   Second Affiliated Hospital, School of Medicine, Zhejiang University

PLAsma Genomic Testing in Patients With Advanced Non-Small Cell Lung Cancer: The PLAN Study

Condition:   Non-small Cell Lung Cancer
Intervention:   Diagnostic Test: ctDNA liquid biopsy - Roche Avenio Assay
Sponsor:   Royal College of Surgeons, Ireland
Not yet recruiting

Longitudinal Sample Collection to Investigate Adaptation and Evolution of Ovarian High-grade Serous Carcinoma

Conditions:   Ovarian Cancer;   High Grade Serous Carcinoma;   Carcinosarcoma, Ovarian;   Fallopian Tube Cancer;   Primary Peritoneal Carcinoma;   BRCA1 Mutation;   BRCA2 Mutation
Sponsors:   Liz-Anne Lewsley;   Ovarian Cancer Action

Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal

Conditions:   Hematopoietic and Lymphoid System Neoplasm;   Metastatic Malignant Solid Neoplasm
Interventions:   Procedure: Biopsy Specimen;   Procedure: Biospecimen Collection;   Other: Medical Chart Review
Sponsor:   Mayo Clinic