Precision Health Clinical Trials

Clinical Application of Non-invasive PGT-A

Condition:   Genetic Testing
Interventions:   Diagnostic Test: PGT-A;   Diagnostic Test: non-invasive PGT-A
Sponsors:   Kaohsiung Veterans General Hospital.;   Sofiva Genomics Co., Ltd.

Circulating Tumor DNA Enriched, Genomically Directed Post-neoadjuvant Trial for Patients With Residual Triple Negative Breast Cancer

Conditions:   Breast Cancer;   Triple Negative Breast Cancer
Interventions:   Drug: Capecitabine;   Drug: Talazoparib;   Drug: Atezolizumab;   Drug: Inavolisib;   Other: Treatment of Choice
Sponsors:   Bryan Schneider, MD;   Genentech, Inc.;   Pfizer;   Foundation Medicine;   Indiana University;   Epic Sciences;   Vera Bradley Foundation for Breast Cancer Research

Multi-layer Data to Improve Diagnosis, Predict Therapy Resistance and Suggest Targeted Therapies in HGSOC

Condition:   High Grade Ovarian Serous Adenocarcinoma
Interventions:   Genetic: WGS and RNA sequencing;   Genetic: circulating tumor DNA (ctDNA);   Diagnostic Test: FDG PET/CT imaging
Sponsors:   Turku University Hospital;   University of Helsinki

Decision-making of ctDNA in Patients With mCRC After Failure of First-line Treatment Containing Cetuximab - a Single-center, Phase II Clinical Study

Condition:   Metastatic Colorectal Cancer
Intervention:   Drug: Cetuximab Ab; Bevacizumab; Vermofenib + cetuximab;Trastuzumab+lapatinib or trastuzumab+pertuzumab; others
Sponsor:   Fudan University
Not yet recruiting

Genetic Diversity of Toxoplasma Gondii in Cancer Patients

Conditions:   Toxoplasma Gondii Infection;   Cancer
Interventions:   Diagnostic Test: ELISA;   Diagnostic Test: PCR;   Diagnostic Test: Sequencing
Sponsor:   Sohag University

Vascular Anomaly Pathology and Genomics Biopsy Study

Conditions:   Vascular Malformations;   Vascular Anomaly;   Hemangioma;   Arteriovenous Malformations;   Venous Malformation;   Klippel Trenaunay Syndrome;   Lymphatic Malformation
Intervention:   Procedure: Percutaneous Vascular Anomaly/Malformation Biopsy
Sponsor:   Mayo Clinic

Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives

Condition:   Channelopathies
Intervention:   Genetic: Genetic analysis
Sponsor:   D'Or Institute for Research and Education

Pembrolizumab and Olaparib in Recurrent/Metastatic, Platinum Resistant Nasopharyngeal Cancer

Condition:   Nasopharyngeal Carcinoma
Intervention:   Drug: Pembrolizumab
Sponsor:   Gruppo Oncologico del Nord-Ovest

Circulating Tumor DNA in Primary Mediastinal Large B-cell Lymphoma (PMBL)

Condition:   Primary Mediastinal Large B-cell Lymphoma
Intervention:   Other: Circulating tumor DNA monitoring
Sponsor:   Centre Henri Becquerel

Epidemiology of Gout in French Polynesia

Condition:   Gout
Intervention:   Other: Epidemiological study
Sponsors:   Lille Catholic University;   Variant Bio, Inc.;   University of Birmingham;   University of San Diego;   Ministry of Health, French Polynesia
Not yet recruiting