Precision Health Clinical Trials

Clinical Trial Multi-analyte Blood Test

Condition:   Liver Cirrhosis
Intervention:   Diagnostic Test: Multi-analyte blood Test
Sponsor:   Helio Genomics

Establishment of Molecular Classification Models for Early Diagnosis of Digestive System Cancers

Conditions:   Esophageal Cancer;   Gastric (Stomach) Cancer;   Colorectal Cancer;   Hepatocellular Carcinoma
Sponsors:   Singlera Genomics Inc.;   Fudan University;   Shanghai Public Health Clinical Center;   Xuhui Central Hospital, Shanghai;   Shanghai Zhongshan Hospital

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Conditions:   Locally Advanced Leiomyosarcoma;   Locally Advanced Uterine Corpus Leiomyosarcoma;   Metastatic Leiomyosarcoma;   Metastatic Uterine Corpus Leiomyosarcoma;   Stage III Uterine Corpus Leiomyosarcoma AJCC v8;   Stage IV Uterine Corpus Leiomyosarcoma AJCC v8;   Unresectable Leiomyosarcoma;   Unresectable Uterine Corpus Leiomyosarcoma;   Uterine Corpus Leiomyosarcoma
Interventions:   Drug: Olaparib;   Drug: Pazopanib;   Drug: Temozolomide;   Drug: Trabectedin
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

Assessment the Cancer Risk of Indeterminate Thyroid Nodules Through Integration of Clinical, Ultrasonographic and Multiomic Features

Conditions:   Thyroid Nodule;   Thyroid Cancer
Intervention:   Diagnostic Test: Multiomic analyses of blood and surgical specimens
Sponsors:   University of Cagliari;   Prof. Pietro Giorgio Calò;   Dott. Gian Luigi Canu
Not yet recruiting

Pneumococcal Carriage and Serotype Distribution in Children With Otitis Media in Malaysia.

Conditions:   Streptococcus Pneumonia;   Otitis Media
Sponsors:   International Medical University;   International Islamic University Malaysia;   Universiti Putra Malaysia;   University of Southampton;   Merck Sharp & Dohme LLC;   Hospital Serdang

Precise Therapy for Refractory HER2 Positive Advanced Breast Cancer

Condition:   HER2+ Breast Cancer
Interventions:   Drug: Trastuzumab;   Drug: Pertuzumab;   Drug: Nab paclitaxel;   Drug: Pyrotinib;   Drug: Capecitabine;   Drug: T-DM1;   Drug: Everolimus;   Drug: CDK4/6 inhibitor;   Drug: AI;   Drug: Anti-PD-1 monoclonal antibody
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University

The Analysis of Gene Variants Related to POCD in Elderly Patients

Condition:   Cognitive Dysfunction
Intervention:   Procedure: Urologic Surgery
Sponsor:   Istanbul University
Not yet recruiting

Prediction of Postoperative Treatment Efficacy and Recurrence Risk of High-risk GIST Based on Minimal Residual Disease Detected by Liquid Biopsy

Conditions:   Gastrointestinal Stromal Tumors;   Minimal Residual Disease
Intervention:   Diagnostic Test: liquid biopsy
Sponsor:   Peking University People's Hospital

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

Conditions:   Breast Cancer;   Colorectal Cancer;   Pancreas Cancer;   Kidney Cancer;   Prostate Cancer;   Ovary Cancer;   Head and Neck Cancer;   Leukemia;   Lymphoma;   Lung Cancer;   Melanoma;   Solid Tumor
Sponsors:   University Health Network, Toronto;   Princess Margaret Hospital, Canada;   Ontario Institute for Cancer Research;   Terry Fox Research Institute

Diabetic Ketoacidosis From New SGLT2i: Can Genomics Estimate Risk

Conditions:   Diabetes Type 2;   DKA;   Diabetic Ketoacidosis
Intervention:   Genetic: Genomic analysis
Sponsors:   Mount Sinai Hospital, Canada;   Unity Health Toronto;   University Health Network, Toronto;   Sault Area Hospital