Precision Health Clinical Trials

Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities. CHROmosome MAPping and Sequencing (CHROMAPS)

Conditions:   Infertility;   Intellectual Disability;   Malformation
Interventions:   Genetic: Optical Genome Mapping (Bionano®);   Genetic: Longread sequencing (Nanopore®)
Sponsor:   Institut National de la Santé Et de la Recherche Médicale, France
Not yet recruiting

Effect of Genetic Polymorphisms of UGT on the PKs of Indapamide in Egyptians

Condition:   Pharmacogenomics
Intervention:   Drug: Indapamide 1.5 MG SR
Sponsor:   Ain Shams University
Not yet recruiting

The Hong Kong Diabetes Biobank

Conditions:   Diabetes Mellitus;   Type 2 Diabetes;   Type 1 Diabetes;   Diabetic Nephropathies;   Diabetic Kidney Disease;   Diabetic Angiopathies;   Cardiovascular Diseases;   Coronary Heart Disease;   Diabetic Retinopathy;   Stroke;   Diabetes
Sponsor:   Chinese University of Hong Kong

Comparison of EPM-IX to Currently Used Specimen Transportation and Extraction Devices ( CGI-EPM-IX )

Condition:   SARS-CoV-2
Intervention:   Diagnostic Test: Enhanced Preservation Media (EPM-IX)
Sponsor:   Convergent Genomics, Inc.

Prephage - Faecal Bacteriophage Transfer for Enhanced Gastrointestinal Tract Maturation in Preterm Infants - Donor Study

Conditions:   Feeding Patterns;   Microbial Colonization
Sponsors:   Rigshospitalet, Denmark;   Lise Aunsholt, Neonatologist, Clinical Professor

Tempus Sculptor Study: Small Cell Lung Cancer (SCLC) Observational Study

Condition:   Small Cell Lung Cancer
Intervention:   Other: Observation
Sponsors:   Tempus Labs;   AstraZeneca

Danish Elder Lymphoma Patient Hematopoietic Investigation

Conditions:   Lymphoma;   Chemotherapy-induced Neutropenia;   Chemotherapy-Related Leukemia;   Chemotherapeutic Toxicity
Intervention:   Diagnostic Test: DNA repair gene mutation analysis
Sponsors:   Rigshospitalet, Denmark;   Tarec C. El-Galaly, Aaalborg University Hospital, Aalborg, Denmark;   Thomas Stauffer Larsen, Odense University Hospital, Odense, Denmark;   Judit M. Jørgensen, Aarhus University Hospital, Aarhus, Denmark;   Troels Møller Thomsen, Gødstrup Regional Hospital, Gødstrup, Denmark;   Michael Thorsgaard, Vejle University Hospital, Vejle, Denmark;   Andriette Dessau-Arp, Southern Jutland University Hospital, Esbjerg, Denmark;   Jacek A. Kisielewicz, Sønderborg Regional Hospital, Sønderborg, Denmark;   Kathrine Grell, Danish Cancer Society, Copenhagen, Denmark;   Lars Møller Pedersen, Zealand University Hospital, Roskilde, Denmark;   Peter Brown, Rigshospitalet, Copenhagen, Denmark;   Kirsten Grønbæk, Rigshospitalet, Copenhagen, Denmark;   Jack Cowland, Rigshospitalet, Copenhagen, Denmark;   Mette Klarskov Andersen, Rigshospitalet, Copenhagen, Denmark

Biological Underpinnings of Socio-emotional Regulation in Preterm Infants and Healthy Controls

Conditions:   Preterm Birth;   Parent-Child Relations;   Epigenetics
Interventions:   Diagnostic Test: DNA methylation of target genes;   Diagnostic Test: EEG acquisition
Sponsor:   IRCCS Eugenio Medea

Artificial Intelligence for Help Non-Small Cell Lung Cancer: Measure Cancer Biology and Treatment Response Via Imaging

Condition:   Non Small Cell Lung Cancer
Intervention:   Procedure: Liquid biopsy
Sponsors:   OncoRadiomics;   University Hospital, Antwerp
Not yet recruiting

Tumor-Agnostic Precision Immuno-Oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study

Condition:   Solid Tumors
Interventions:   Drug: Entrectinib;   Drug: Alectinib;   Drug: Atezolizumab;   Drug: Ipatasertib;   Drug: Trastuzumab emtansine;   Drug: Idasanutlin;   Drug: Inavolisib;   Drug: Belvarafenib;   Drug: Pralsetinib;   Drug: GDC-6036;   Drug: Camonsertib
Sponsor:   Hoffmann-La Roche