Precision Health Clinical Trials

Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities. CHROmosome MAPping and Sequencing (CHROMAPS)

Conditions:   Infertility;   Intellectual Disability;   Malformation
Interventions:   Genetic: Optical Genome Mapping (Bionano®);   Genetic: Longread sequencing (Nanopore®)
Sponsor:   Institut National de la Santé Et de la Recherche Médicale, France
Not yet recruiting

For more information, visit the Study URL.

Effect of Genetic Polymorphisms of UGT on the PKs of Indapamide in Egyptians

Condition:   Pharmacogenomics
Intervention:   Drug: Indapamide 1.5 MG SR
Sponsor:   Ain Shams University
Not yet recruiting

For more information, visit the Study URL.

The Hong Kong Diabetes Biobank

Conditions:   Diabetes Mellitus;   Type 2 Diabetes;   Type 1 Diabetes;   Diabetic Nephropathies;   Diabetic Kidney Disease;   Diabetic Angiopathies;   Cardiovascular Diseases;   Coronary Heart Disease;   Diabetic Retinopathy;   Stroke;   Diabetes
Intervention:  
Sponsor:   Chinese University of Hong Kong
Recruiting

For more information, visit the Study URL.

Comparison of EPM-IX to Currently Used Specimen Transportation and Extraction Devices ( CGI-EPM-IX )

Condition:   SARS-CoV-2
Intervention:   Diagnostic Test: Enhanced Preservation Media (EPM-IX)
Sponsor:   Convergent Genomics, Inc.
Recruiting

For more information, visit the Study URL.

Prephage - Faecal Bacteriophage Transfer for Enhanced Gastrointestinal Tract Maturation in Preterm Infants - Donor Study

Conditions:   Feeding Patterns;   Microbial Colonization
Intervention:  
Sponsors:   Rigshospitalet, Denmark;   Lise Aunsholt, Neonatologist, Clinical Professor
Recruiting

For more information, visit the Study URL.

Tempus Sculptor Study: Small Cell Lung Cancer (SCLC) Observational Study

Condition:   Small Cell Lung Cancer
Intervention:   Other: Observation
Sponsors:   Tempus Labs;   AstraZeneca
Recruiting

For more information, visit the Study URL.

Danish Elder Lymphoma Patient Hematopoietic Investigation

Conditions:   Lymphoma;   Chemotherapy-induced Neutropenia;   Chemotherapy-Related Leukemia;   Chemotherapeutic Toxicity
Intervention:   Diagnostic Test: DNA repair gene mutation analysis
Sponsors:   Rigshospitalet, Denmark;   Tarec C. El-Galaly, Aaalborg University Hospital, Aalborg, Denmark;   Thomas Stauffer Larsen, Odense University Hospital, Odense, Denmark;   Judit M. Jørgensen, Aarhus University Hospital, Aarhus, Denmark;   Troels Møller Thomsen, Gødstrup Regional Hospital, Gødstrup, Denmark;   Michael Thorsgaard, Vejle University Hospital, Vejle, Denmark;   Andriette Dessau-Arp, Southern Jutland University Hospital, Esbjerg, Denmark;   Jacek A. Kisielewicz, Sønderborg Regional Hospital, Sønderborg, Denmark;   Kathrine Grell, Danish Cancer Society, Copenhagen, Denmark;   Lars Møller Pedersen, Zealand University Hospital, Roskilde, Denmark;   Peter Brown, Rigshospitalet, Copenhagen, Denmark;   Kirsten Grønbæk, Rigshospitalet, Copenhagen, Denmark;   Jack Cowland, Rigshospitalet, Copenhagen, Denmark;   Mette Klarskov Andersen, Rigshospitalet, Copenhagen, Denmark
Recruiting

For more information, visit the Study URL.

Biological Underpinnings of Socio-emotional Regulation in Preterm Infants and Healthy Controls

Conditions:   Preterm Birth;   Parent-Child Relations;   Epigenetics
Interventions:   Diagnostic Test: DNA methylation of target genes;   Diagnostic Test: EEG acquisition
Sponsor:   IRCCS Eugenio Medea
Recruiting

For more information, visit the Study URL.

Artificial Intelligence for Help Non-Small Cell Lung Cancer: Measure Cancer Biology and Treatment Response Via Imaging

Condition:   Non Small Cell Lung Cancer
Intervention:   Procedure: Liquid biopsy
Sponsors:   OncoRadiomics;   University Hospital, Antwerp
Not yet recruiting

For more information, visit the Study URL.

Tumor-Agnostic Precision Immuno-Oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study

Condition:   Solid Tumors
Interventions:   Drug: Entrectinib;   Drug: Alectinib;   Drug: Atezolizumab;   Drug: Ipatasertib;   Drug: Trastuzumab emtansine;   Drug: Idasanutlin;   Drug: Inavolisib;   Drug: Belvarafenib;   Drug: Pralsetinib;   Drug: GDC-6036;   Drug: Camonsertib
Sponsor:   Hoffmann-La Roche
Recruiting

For more information, visit the Study URL.

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