Precision Health Clinical Trials

Tempus NSCLC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With NSCLC Using NGS Assays

Condition:   Non-Small Cell Lung Cancer
Intervention:   Other: Observation
Sponsor:   Tempus Labs

Cellular-Mediated Immunity in COVID-19

Conditions:   Covid19;   Thromboembolism
Interventions:   Diagnostic Test: Multitest 6 color TBNK and BD Lyotubes;   Biological: genomicDNA extraction
Sponsor:   University of Campania "Luigi Vanvitelli"

Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

Condition:   Colorectal Cancer
Intervention:   Other: Observation
Sponsor:   Tempus Labs

GWAS in NMDAR Encephalitis

Condition:   Autoimmune Encephalitis
Intervention:   Genetic: GWAS
Sponsor:   Hospices Civils de Lyon

Genomics of Fibrin Clot Structure in Patients With Constitutional Dysfibrinogenemia

Condition:   Hereditary Dysfibrinogenemia
Intervention:   Biological: Blood test
Sponsor:   University Hospital, Clermont-Ferrand

DNA Sequencing in Clinical Practice, Mayo Clinic Health Tapestry Study

Condition:   Genetic Disorder
Interventions:   Procedure: Biospecimen Collection;   Other: Diagnostic Laboratory Biomarker Analysis;   Other: Genetic Counseling;   Other: Questionnaire Administration
Sponsor:   Mayo Clinic

The Predictive Capacity of Machine Learning Models for Progressive Kidney Disease in Individuals With Sickle Cell Anemia

Conditions:   Sickle Cell Disease;   Kidney Diseases, Chronic
Intervention:   Other: Biospecimen/DNA collection and analysis
Sponsors:   University of Tennessee;   National Heart, Lung, and Blood Institute (NHLBI);   University of Illinois at Chicago;   University of Memphis;   University of North Carolina, Charlotte;   Wake Forest University;   University of North Carolina, Chapel Hill

Clinical Performance Evaluation of the C2i-Test

Condition:   Muscle-Invasive Bladder Carcinoma
Intervention:   Diagnostic Test: C2i Test
Sponsors:   C2i Genomics;   New Jersey Urology;   University of Texas;   Baylor College of Medicine;   NY Health d/b/a New York Cancer and Blood Specialists;   The Cleveland Clinic;   Fox Chase Cancer Center;   New York University;   University of Washington;   Oregon Health and Science University;   University of Southern California;   Ohio State University

Multimodal Imaging Based on Pathological and Genomic Characteristics

Conditions:   Mitochondrial DNA Mutation;   Endoscopy
Intervention:   Other: Patients diagnosed as gastrointestinal mucosal lesions
Sponsor:   Affiliated Hospital to Academy of Military Medical Sciences

Prediction Model for Response to Biologics and Small Molecular Agent for UC

Condition:   Ulcerative Colitis
Intervention:   Drug: Vedolizumab, Ustekinumab, or Tofacitinib
Sponsor:   Asan Medical Center