Precision Health Clinical Trials

Intestinal Microbiome Composition in Infants With Biliary Atresia (BA)

Conditions:   Biliary Atresia;   Intrahepatic Cholestases;   Normal Controls
Sponsors:   Children's Hospital Medical Center, Cincinnati;   Wuhan Union Hospital, China
Not yet recruiting

Clinical, Molecular and Functional Biomarkers for PROgnosis, Pathomechanisms and Treatment Strategies of COVID-19

Condition:   COVID-19 Pneumonia
Sponsors:   Charite University, Berlin, Germany;   German Federal Ministry of Education and Research;   University of Leipzig;   University of Jena

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Conditions:   Schizophrenia;   Cannabis Dependence;   Prodromal for Psychotic Illness;   Family History of Alcoholism;   Healthy Control;   Opioid-use Disorder;   Post Traumatic Stress Disorder
Intervention:   Radiation: [11-C]OMAR
Sponsors:   Yale University;   National Institute on Drug Abuse (NIDA);   National Institute of Mental Health (NIMH)

Screening of Susceptibility Genes for APAP Induced Drug Induced LIver Injury in ChiNese Population: a Case-control Study

Conditions:   Acetaminophen;   Drug-Induced Liver Injury;   Pharmacogenetics;   China
Intervention:   Genetic: genetic polymorphism
Sponsors:   The First Affiliated Hospital with Nanjing Medical University;   University of Colorado, Denver;   Beijing Genomics Institute;   Nanjing Medical University

Phenotype and Prognosis of Patients With Breast Cancer and Pathogenic Variants of TP53

Conditions:   Breast Cancer;   TP53 R337H;   Li-Fraumeni Syndrome;   Prognosis Breast Cancer
Intervention:   Other: No intervention in this study
Sponsor:   Instituto do Cancer do Estado de São Paulo

Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy

Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myeloproliferative Syndrome
Intervention:   Genetic: Genomic profiling
Sponsors:   Dana-Farber Cancer Institute;   Charles H. Hood Foundation

HypErsensitiVity PneumonITis: DiseAse Progression Characterization

Condition:   Hypersensitivity Pneumonitis
Intervention:   Other: Disease assessment
Sponsors:   Hospital do Coracao;   Boehringer Ingelheim;   Centro Rossi, Buenos Aires, Argentina

The Association Between LPCAT1 Genetic Polymorphism and Stress Biomarkers in Neonatal Respiratory Distress Syndrome

Condition:   Neonatal Respiratory Distress
Intervention:   Diagnostic Test: stress biomarkers
Sponsor:   Assiut University

BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial

Conditions:   Brain Neoplasms;   Liquid Biopsy
Interventions:   Procedure: Magnetic Resonance Guided Focused Ultrasound Tumor Ablation and Liquid Biopsy Acquisition;   Procedure: Magnetic Resonance Guided Focused Ultrasound Thalamotomy
Sponsors:   University Health Network, Toronto;   Canadian Cancer Society (CCS);   Brain Canada

Retrospective Comparative in Vitro Case-controlled Study of the Liquid Biopsy Test System in Women With Breast Cancer

Condition:   Breast Neoplasm Female
Intervention:   Diagnostic Test: ARNA Breast
Sponsors:   ARNA Genomics US Inc.;   BIOMARKER-RU