Precision Health Clinical Trials

A Phase 1 Trial of the p97 Inhibitor CB-5339 in Patients With Advanced Solid Tumors and Lymphomas

Conditions:   Advanced Solid Tumors;   Advanced Lymphomas
Intervention:   Drug: CB-5339
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Condition:   Neoplasms
Interventions:   Drug: Nilotinib;   Drug: Paclitaxel
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

Evaluation of Clinical, Radiomics and Molecular Features of Lung Metastasis in PDAC Patients (LUMACA Trial)

Condition:   Pancreas Adenocarcinoma
Interventions:   Genetic: Analysis of genetic mutations and the gene expression profile of lung metastasis and primary neoplasia;   Other: Radiomics analysis on TAC imaging at diagnosis of lung metastasis and, if possible, of the primary tumor
Sponsor:   IRCCS San Raffaele

Follow-up of Patients With Uveal Melanoma Adapted to the Risk of Relapse (SALOME)

Condition:   Uveal Melanoma
Intervention:   Other: Blood test
Sponsor:   Institut Curie

ImmuneSense Lyme Study

Condition:   Lyme Disease
Intervention:   Diagnostic Test: T-Detect Lyme
Sponsors:   Adaptive Biotechnologies;   Iqvia Pty Ltd

Histological, Genetic and Epigenetic Analysis of Procedures Related With Dental Implants

Conditions:   Peri-Implantitis;   Peri-implant Mucositis;   Implant Complication;   Implant Tissue Failure
Interventions:   Procedure: Gingival and bone sample collection;   Procedure: Healthy individuals
Sponsors:   Simón Pardiñas López;   NYU Langone Health;   Göteborg University;   University Hospital A Coruña;   Instituto de Investigacion Biomedica de A Coruna

Epigenetic Tools as Prognostic Predictors in Covid19

Condition:   Prognosis
Intervention:   Other: Taking biological samples
Sponsors:   Bakirkoy Dr. Sadi Konuk Research and Training Hospital;   Istanbul University

Determining the Reproductive Health of Men Post-COVID-19 Infection

Conditions:   Infertility, Male;   Testosterone Deficiency
Intervention:   Other: Exposure: Covid-19 infection
Sponsor:   Imperial College London
Not yet recruiting

Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders

Condition:   Sickle Cell Disease
Sponsors:   St. Jude Children's Research Hospital;   National Heart, Lung, and Blood Institute (NHLBI)

Assessement of the Concordance of Genomic Alterations Between Urine and Tissue in High-Risk NMIBC Patients

Condition:   Bladder Cancer
Sponsors:   Hopital Foch;   AstraZeneca