Precision Health Clinical Trials

Decision-making of ctDNA in Patients With mCRC After Failure of First-line Treatment Containing Cetuximab - a Single-center, Phase II Clinical Study

Condition:   Metastatic Colorectal Cancer
Intervention:   Drug: Cetuximab Ab; Bevacizumab; Vermofenib + cetuximab;Trastuzumab+lapatinib or trastuzumab+pertuzumab; others
Sponsor:   Fudan University
Not yet recruiting

Genetic Diversity of Toxoplasma Gondii in Cancer Patients

Conditions:   Toxoplasma Gondii Infection;   Cancer
Interventions:   Diagnostic Test: ELISA;   Diagnostic Test: PCR;   Diagnostic Test: Sequencing
Sponsor:   Sohag University

Vascular Anomaly Pathology and Genomics Biopsy Study

Conditions:   Vascular Malformations;   Vascular Anomaly;   Hemangioma;   Arteriovenous Malformations;   Venous Malformation;   Klippel Trenaunay Syndrome;   Lymphatic Malformation
Intervention:   Procedure: Percutaneous Vascular Anomaly/Malformation Biopsy
Sponsor:   Mayo Clinic

Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives

Condition:   Channelopathies
Intervention:   Genetic: Genetic analysis
Sponsor:   D'Or Institute for Research and Education

Pembrolizumab and Olaparib in Recurrent/Metastatic, Platinum Resistant Nasopharyngeal Cancer

Condition:   Nasopharyngeal Carcinoma
Intervention:   Drug: Pembrolizumab
Sponsor:   Gruppo Oncologico del Nord-Ovest

Circulating Tumor DNA in Primary Mediastinal Large B-cell Lymphoma (PMBL)

Condition:   Primary Mediastinal Large B-cell Lymphoma
Intervention:   Other: Circulating tumor DNA monitoring
Sponsor:   Centre Henri Becquerel

Epidemiology of Gout in French Polynesia

Condition:   Gout
Intervention:   Other: Epidemiological study
Sponsors:   Lille Catholic University;   Variant Bio, Inc.;   University of Birmingham;   University of San Diego;   Ministry of Health, French Polynesia
Not yet recruiting

Epigenetics and Protective Factors in the Preterm Infant

Conditions:   Preterm Birth;   Parent-Child Relations;   Epigenetics
Interventions:   Genetic: DNA methylation of target genes;   Diagnostic Test: Functional Magnetic Resonance Imaging (fMRI) acquisition
Sponsor:   IRCCS Eugenio Medea

Phenomics and Genomics of Clinically Relevant Chronic Postsurgical Pain

Conditions:   Chronic Pain;   Surgery
Sponsor:   University Health Network, Toronto

Oncodrivers in Malignant Pleural Effusions Associated With Non-small Cell Lung Cancer: A Prospective Study.

Conditions:   Malignant Pleural Effusion;   Non-small Cell Lung Cancer
Intervention:   Diagnostic Test: meassurement of PD-L1, ALK, EGFR
Sponsor:   Naestved Hospital