Precision Health Clinical Trials

Evaluation ctDNA in Patients of Non-Small-Cell Lung Cancer Following Resection

Condition:   Non-Small Cell Lung Cancer
Intervention:   Diagnostic Test: Perioperative ctDNA Dynamic Monitoring
Sponsors:   Sun Yat-sen University;   Hangzhou Repugene Technology Co., Ltd.
Recruiting

Genotypic Influences on Network Progression in Parkinson's Disease

Condition:   Parkinson's Disease
Interventions:   Genetic: DNA/GeneticTesting;   Radiation: FDG PET scan;   Other: MRI scan;   Other: Clinical and neuropsychological assessments
Sponsors:   Northwell Health;   Michael J. Fox Foundation for Parkinson's Research;   The Silverstein Foundation for Parkinson's with GBA
Recruiting

Uro-DNA Collection for Expanded Genome-Wide Association Study (GWAS) of Renal Cell Carcinoma (RCC)

Condition:   Kidney Cancer
Interventions:   Procedure: Intervention in the UroCCR sites;   Procedure: Intervention in the CRB of Bordeaux University Hospital;   Procedure: Intervention at the Methodology and Data Management Centre of Bordeaux University Hospital;   Procedure: Subsequent intervention at the NCI (for information)
Sponsors:   University Hospital, Bordeaux;   National Cancer Institute (NCI)
Recruiting

Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan

Condition:   Hearing Disorder
Intervention:  
Sponsor:   National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting

Development of a Predictive Model for Early Differential Diagnosis of Uterine Leiomyomas and Leiomyosarcomas

Conditions:   Leiomyoma;   Leiomyosarcoma
Intervention:   Procedure: Biopsy and peripheral blood collection
Sponsor:   Igenomix
Recruiting

Personalized Medicine Program on Myelodysplastic Syndromes: Characterization of the Patient's Genome for Clinical Decision Making and Systematic Collection of Real World Data to Improve Quality of Health Care

Condition:   MDS (Myelodysplastic Syndrome)
Intervention:  
Sponsor:   Fondazione Italiana Sindromi Mielodisplastiche-ETS
Recruiting

FATLAS: Comprehensive Multi-level Characterization of Systemic and Mammary Adiposity in Breast Cancer Patients.

Condition:   Breast Neoplasms
Intervention:   Other: Prospective data and sample collection
Sponsors:   Universitaire Ziekenhuizen Leuven;   KU Leuven
Recruiting

Analysis of Screen-detected Lung Cancers' Genomic Traits

Condition:   Lung Cancer
Intervention:  
Sponsor:   University College, London
Recruiting

Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

Conditions:   Acute Lymphoblastic Leukemia;   Acute Lymphoblastic Lymphoma
Interventions:   Drug: Prednisone;   Drug: Vincristine;   Drug: Daunorubicin;   Drug: Pegaspargase;   Drug: Erwinase®;   Drug: Cyclophosphamide;   Drug: Cytarabine;   Drug: Mercaptopurine;   Drug: Dasatinib;   Drug: Methotrexate;   Drug: Blinatumomab;   Drug: Ruxolitinib;   Drug: Bortezomib;   Drug: Dexamethasone;   Drug: Doxorubicin;   Drug: Etoposide;   Drug: Clofarabine;   Drug: Vorinostat;   Drug: Idarubicin;   Drug: Nelarabine;   Drug: Thioguanine;   Drug: Asparaginase Erwinia chrysanthemi (recombinant)-rywn
Sponsors:   St. Jude Children's Research Hospital;   Incyte Corporation;   Amgen;   Servier
Recruiting

Genomics in Infection and Sepsis to Predict Organ Dysfunction and Outcomes in Sepsis

Conditions:   Sepsis;   Infection;   Pneumonia
Intervention:  
Sponsor:   Chinese University of Hong Kong
Recruiting

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