Precision Health Clinical Trials

Trifecta-Heart cfDNA-MMDx Study

Condition:   Heart Transplant Rejection
Interventions:   Diagnostic Test: MMDx diagnostic test;   Diagnostic Test: Prospera;   Diagnostic Test: HLA antibody
Sponsors:   University of Alberta;   Natera, Inc.;   One Lambda
Recruiting

For more information, visit the Study URL.

Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve

Condition:   Diminished Ovarian Reserve
Intervention:   Other: whole-genome sequencing
Sponsors:   Nanfang Hospital of Southern Medical University;   Ferring Pharmaceuticals
Recruiting

For more information, visit the Study URL.

LIQUIK: LIQUId Biopsy for Detection of Actionable Genomic BiomarKers in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)

Condition:   Non Small Cell Lung Cancer
Intervention:  
Sponsor:   Lucence Health Inc.
Recruiting

For more information, visit the Study URL.

A Trial for Relapsed and Relapsed/Refractory Multiple Myeloma Patients

Conditions:   Multiple Myeloma;   Deletion 17P Syndrome
Interventions:   Drug: Daratumumab;   Drug: Pomalidomide;   Drug: Dexamethasone
Sponsor:   Fondazione EMN Italy Onlus
Recruiting

For more information, visit the Study URL.

Testing Tumor Tissue and Blood to Help Select Personalized Treatments for Patients With Suspected Lung Cancers

Condition:   NSCLC
Intervention:   Diagnostic Test: ctDNA, tumor NGS
Sponsors:   Lung Cancer Mutation Consortium;   Lung Cancer Research Foundation
Recruiting

For more information, visit the Study URL.

A Pharmacodynamics-Driven Trial of Talazoparib, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Aberrations in Genes Involved in DNA Damage Response

Condition:   Solid Tumors
Intervention:   Drug: talazoparib
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

For more information, visit the Study URL.

Genomic Study of Relapse Esophageal Cancer After Radiotherapy

Conditions:   Gene Mutation-Related Cancer;   Esophageal Cancer;   Radiation Exposure
Intervention:   Genetic: whole exome sequence
Sponsors:   Fudan University;   M.D. Anderson Cancer Center;   Nantong University;   Jiangsu Cancer Institute & Hospital;   Henan Cancer Hospital;   Ningbo No.2 Hospital;   Taihe Hospital;   Taian Cancer Hospital
Recruiting

For more information, visit the Study URL.

Research of Pathological Imaging Diagnosis of Ocular Tumors Based on New Artificial Intelligence Algorithm

Conditions:   Melanoma (Skin);   Melanoma in Situ;   Nevus Eye;   Sebaceous Gland Carcinoma of the Eyelid;   Basal Cell Carcinoma;   Squamous Cell Carcinoma in Situ;   Ocular Tumor
Intervention:  
Sponsor:   Peking University
Not yet recruiting

For more information, visit the Study URL.

Genetic Polymorphisms and Their Association With Temporomandibular Disorders

Conditions:   Temporomandibular Disorders;   Orofacial Pain
Interventions:   Device: stabilization splint;   Procedure: physical therapy;   Device: placebo splint
Sponsor:   Croatian Science Foundation
Recruiting

For more information, visit the Study URL.

AntiCMV molécules Monitoring in Real-life in Stem Cell Recipients

Conditions:   Hematopoietic Stem Cell Transplantation;   Cytomegalovirus Infections;   Antivirals;   Antiviral Drug Resistance
Intervention:   Other: Real-life observatory of efficacy and resistance to anti CMV molecules in stem cell recipients
Sponsor:   University Hospital, Limoges
Recruiting

For more information, visit the Study URL.

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