Precision Health Clinical Trials

Russian Disc Degeneration Study

Conditions:   Intervertebral Disc Degeneration;   Genetic Predisposition to Disease
Intervention:   Other: Non-interventional
Sponsors:   Novosibirsk State University;   Institute of Cytology and Genetics;   Novosibirsk Research Institute of Traumatology and Orthopaedics n.a. Ya.L. Tsivyan;   N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

OneinSeven Gestational Diabetes Genetic and Socioeconomic Risk Study

Conditions:   Gestational Diabetes;   Pregnancy Complications;   Pregnancy Related;   Genetic Predisposition;   Risk Reduction
Intervention:   Genetic: Polygenic Risk Score Generation
Sponsor:   Prenome

Developing a Test for the Detection of Ovarian Cancer

Conditions:   Ovarian Neoplasms;   Ovarian Epithelial Carcinoma;   Fallopian Tube Neoplasms;   High Grade Ovarian Serous Adenocarcinoma;   Stage I Ovarian Cancer;   Stage II Ovarian Cancer;   Stage III Ovarian Cancer AJCC v8;   Stage IIIA Ovarian Cancer AJCC v8;   Stage IIIA1 Ovarian Cancer AJCC v8;   Stage IIIA2 Ovarian Cancer AJCC v8;   Stage IIIB Ovarian Cancer AJCC v8;   Stage IIIC Ovarian Cancer AJCC v8;   Stage IV Ovarian Cancer AJCC v8;   Stage IVA Ovarian Cancer AJCC v8;   Stage IVB Ovarian Cancer AJCC v8
Interventions:   Diagnostic Test: Uterine lavage, or a wash of the womb;   Diagnostic Test: Blood sample;   Diagnostic Test: Pap smear
Sponsors:   Massachusetts General Hospital;   Johns Hopkins University;   Fred Hutchinson Cancer Center;   Anne Arundel Health System Research Institute;   University of Arkansas;   National Cancer Institute (NCI);   Kaiser Permanente;   McGill University;   M.D. Anderson Cancer Center;   Swedish Medical Center;   TwinStrand Biosciences

EUS Guided HVA and PVA for Circulating Tumor DNA in Patients

Conditions:   Circulating Tumor Cell;   Gastrointestinal Cancer
Intervention:   Diagnostic Test: EUS-guided portal vein and hepatic vein aspiration
Sponsor:   Chinese University of Hong Kong

Motor Impairments in Children With Autism Spectrum Disorder: a Multimodal Approach

Conditions:   Autism Spectrum Disorder;   Attention Deficit Hyperactivity Disorder;   Intellectual Disability
Interventions:   Diagnostic Test: Clinical evaluation;   Diagnostic Test: Neuropsychological evaluation;   Diagnostic Test: Neurophysiological evaluation;   Diagnostic Test: Genetic evaluation
Sponsor:   IRCCS Eugenio Medea

Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast Cancer

Conditions:   Triple Negative Breast Cancer;   Breast Cancer
Intervention:   Drug: Capecitabine
Sponsor:   Stanford University

Study of Leukocyte Populations in Patients With Chronic Inflammatory

Conditions:   Systemic Autoimmune Disease;   Chronic Inflammatory Rheumatism;   Sjogren's Syndrome;   Spondyloarthritis;   Rheumatoid Arthritis;   Systemic Lupus Erythematosus
Intervention:   Other: blood sample
Sponsor:   Assistance Publique - Hôpitaux de Paris
Not yet recruiting

Carcinoma of Unknown Primary (CUP): A Comparison Across Tissue and Liquid Biomarkers

Condition:   Cancer of Unknown Primary Site
Sponsors:   The Christie NHS Foundation Trust;   Hoffmann-La Roche;   ConcR;   Durham University

imPlementing ROutine Molecular Characterization in Patients With Metastatic Castration Resistant ProstaTe Cancer by NGS

Condition:   Metastatic Prostate Cancer
Interventions:   Procedure: Biopsy;   Procedure: Blood sample
Sponsors:   Radboud University Medical Center;   VGZ health insurance (NL);   Paul Speth Foundation (NL);   Radboud Oncology Fund (NL)

Myocardial FIbrosis in Repaired Tetralogy of FAllot- FIFA Study)

Conditions:   Congenital Heart Disease;   Congenital Heart Defect;   Fallot Tetralogy
Intervention:   Other: Non intervention
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute