Precision Health Clinical Trials

HepatoPredict Prognostic Tool for the Decision of Liver Transplant in Hepatocellular Carcinoma

Conditions:   Hepatocellular Carcinoma, Scirrhous;   Recurrence Tumor
Intervention:   Procedure: liver transplant
Sponsors:   Centro Hospitalar de Lisboa Central;   Ophiomics - Precision Medicine
Recruiting

For more information, visit the Study URL.

Genomics and Metagenomics of Asthma Severity

Conditions:   Asthma;   Asthma Attack
Intervention:  
Sponsors:   Maria Pino-Yanes;   University of La Laguna;   Spanish Ministry of Science, Innovation, and Universities;   Consorcio Centro de Investigación Biomédica en Red (CIBER);   University Hospital of the Nuestra Señora de Candelaria;   Hospital Universitario de Canarias;   Hospital General de La Palma;   Hospital Universitario Donostia;   Hospital Doctor Jose Molina Orosa
Recruiting

For more information, visit the Study URL.

Predictors of Better Outcomes After Severe Acquired Brain Injuries

Conditions:   Brain Injuries;   Disorder of Consciousness
Intervention:   Genetic: Genetic analysis of different single nucleotide polymorphisms on ApoE, BDNF and DRD2 genes assessment
Sponsor:   Fondazione Don Carlo Gnocchi Onlus
Recruiting

For more information, visit the Study URL.

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

Condition:   Parkinson Disease
Intervention:  
Sponsors:   Michael J. Fox Foundation for Parkinson's Research;   Institute for Neurodegenerative Disorders
Recruiting

For more information, visit the Study URL.

PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study)

Conditions:   Hepatocellular Cancer;   Cholangiocarcinoma;   Gallbladder Cancer;   Pancreatic Cancer;   Oesophageal Cancer;   Stomach Cancer
Intervention:   Diagnostic Test: FoundationOne®CDx and FoundationOne®Liquid
Sponsors:   Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest;   Roche Pharma AG
Recruiting

For more information, visit the Study URL.

Detection of Genetic Markers of Lung Cancer

Condition:   Lung Cancer
Interventions:   Procedure: Biopsy of the major carinal area;   Procedure: Biopsy of abnormal & suspicious areas of the bronchial tree;   Procedure: Evaluation of the tumor for DNA mutations;   Procedure: Bronchoalveolar Lavage (BAL) for cytokine analysis;   Procedure: Correlation of flow cytometric & RT PCR for TNM stage;   Procedure: Analysis of lymph nodes
Sponsors:   University of Pittsburgh;   National Institutes of Health (NIH)
Recruiting

For more information, visit the Study URL.

Longitudinal Follow-up Study in Two Chinese Hypertension Cohorts

Condition:   Hypertension
Intervention:   Other: Incidence and risk factors of hypertension
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University
Not yet recruiting

For more information, visit the Study URL.

A Phase 1 Trial of the p97 Inhibitor CB-5339 in Patients With Advanced Solid Tumors and Lymphomas

Conditions:   Advanced Solid Tumors;   Advanced Lymphomas
Intervention:   Drug: CB-5339
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

For more information, visit the Study URL.

Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Condition:   Neoplasms
Interventions:   Drug: Nilotinib;   Drug: Paclitaxel
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

For more information, visit the Study URL.

Evaluation of Clinical, Radiomics and Molecular Features of Lung Metastasis in PDAC Patients (LUMACA Trial)

Condition:   Pancreas Adenocarcinoma
Interventions:   Genetic: Analysis of genetic mutations and the gene expression profile of lung metastasis and primary neoplasia;   Other: Radiomics analysis on TAC imaging at diagnosis of lung metastasis and, if possible, of the primary tumor
Sponsor:   IRCCS San Raffaele
Recruiting

For more information, visit the Study URL.

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