Precision Health Clinical Trials

DOAC in Chinese Patients With Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Stroke;   Stroke, Acute;   Brain Diseases;   Major Adverse Cardiovascular Event;   Arterial Thromboembolism;   Venous Thromboembolism
Intervention:   Diagnostic Test: Blood Tests
Sponsor:   Chinese University of Hong Kong
Not yet recruiting

Human Epilepsy Project 3

Condition:   Idiopathic Generalized Epilepsy
Sponsor:   NYU Langone Health

PATH Trial: Personalized Approaches in the Treatment of Head and Neck Cancer

Condition:   Head and Neck Cancer
Intervention:   Diagnostic Test: Whole genomic DNA/RNA tumour sequencing
Sponsor:   British Columbia Cancer Agency
Not yet recruiting

The TIOB - Collection of Patients' Biospecimens for Analysis of Immunological and Molecular Biomarkers.

Condition:   Cancer
Sponsors:   Baylor Research Institute;   Translational Genomics Research Institute

ITGA4 Gene Methylation Status in Chronic Lymphocytic Leukemia

Condition:   Chronic Lymphocytic Leukemia
Sponsor:   Sohag University
Not yet recruiting

Food Intake and Epigenetic Alteration in the Spermatozoa of Singletons and Twins

Conditions:   Fertility Issues;   Nutrition, Healthy;   Epigenetic Disorder;   Overnutrition
Interventions:   Dietary Supplement: Isocaloric Unprocessed Diet;   Dietary Supplement: Isocaloric Processed Diet;   Dietary Supplement: Excess Calorie Unprocessed Diet;   Dietary Supplement: Excess Calorie Processed Diet
Sponsors:   University of Copenhagen;   Deakin University;   Monash Health

The Impact of Probiotic Supplementation on Antibiotic Induced Changes in Gastrointestinal Function and/or Faecal Microbiota Composition

Condition:   Antibiotic Side Effect
Interventions:   Dietary Supplement: LAB4 + Saccharomyces boulardii;   Dietary Supplement: Placebo
Sponsors:   Cultech Ltd;   Comac Medical
Not yet recruiting

Two Biologically and Clinically Distinct Entities: Progressive Versus Stable Multiple Myeloma (MM) Precursor Conditions

Conditions:   Multiple Myeloma;   Smoldering Multiple Myeloma;   Monoclonal Gammopathy of Undetermined Significance
Sponsor:   University of Miami

Spatial Analysis of Host-parasite Interactions in Cutaneous Leishmaniasis in Ethiopia

Condition:   Cutaneous Leishmaniases
Interventions:   Diagnostic Test: skin biopsy;   Diagnostic Test: venous blood sample (plasma, PBMC, WB);   Genetic: venous blood sample (HLA);   Genetic: skin slit
Sponsors:   Institute of Tropical Medicine, Belgium;   University of Gondar;   Wollo University;   University of York;   Maastricht University;   University Hospital, Antwerp

Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITION-GUIDE)

Condition:   Early-stage Breast Cancer
Interventions:   Drug: Atezolizumab 1200 mg in 20 ML Injection;   Drug: Inavolisib;   Drug: Ipatasertib;   Drug: Olaparib;   Drug: Sacituzumab govitecan;   Drug: Trastuzumab/pertuzumab
Sponsor:   German Cancer Research Center
Not yet recruiting