Precision Health Clinical Trials

Parkinson's Foundation PD GENEration Genetic Registry

Condition:   Parkinson's Disease
Intervention:   Device: Lab Assay for seven genetic variants for Parkinson's Disease
Sponsors:   Parkinson's Foundation;   Indiana University;   Fulgent Laboratory;   Parkinson's Study Group

Breast Cancer, Omics, and Precision Medicine

Condition:   Breast Cancer
Intervention:   Biological: Next Generation Sequencing and Network Analysis
Sponsor:   University of Campania "Luigi Vanvitelli"
Not yet recruiting

Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDS

Conditions:   Whole Genome Sequencing;   Acute Myeloid Leukemia;   Myelodysplastic Syndromes
Intervention:   Device: ChromoSeq
Sponsor:   Washington University School of Medicine

Clinical, Molecular and Functional Biomarkers for PROgnosis, Pathomechanisms and Treatment Strategies of COVID-19

Condition:   COVID-19 Pneumonia
Sponsors:   Charite University, Berlin, Germany;   German Federal Ministry of Education and Research;   University of Leipzig;   University of Jena

Intestinal Microbiome Composition in Infants With Biliary Atresia (BA)

Conditions:   Biliary Atresia;   Intrahepatic Cholestases;   Normal Controls
Sponsors:   Children's Hospital Medical Center, Cincinnati;   Wuhan Union Hospital, China
Not yet recruiting

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Conditions:   Schizophrenia;   Cannabis Dependence;   Prodromal for Psychotic Illness;   Family History of Alcoholism;   Healthy Control;   Opioid-use Disorder;   Post Traumatic Stress Disorder
Intervention:   Radiation: [11-C]OMAR
Sponsors:   Yale University;   National Institute on Drug Abuse (NIDA);   National Institute of Mental Health (NIMH)

Screening of Susceptibility Genes for APAP Induced Drug Induced LIver Injury in ChiNese Population: a Case-control Study

Conditions:   Acetaminophen;   Drug-Induced Liver Injury;   Pharmacogenetics;   China
Intervention:   Genetic: genetic polymorphism
Sponsors:   The First Affiliated Hospital with Nanjing Medical University;   University of Colorado, Denver;   Beijing Genomics Institute;   Nanjing Medical University

Phenotype and Prognosis of Patients With Breast Cancer and Pathogenic Variants of TP53

Conditions:   Breast Cancer;   TP53 R337H;   Li-Fraumeni Syndrome;   Prognosis Breast Cancer
Intervention:   Other: No intervention in this study
Sponsor:   Instituto do Cancer do Estado de São Paulo

Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy

Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myeloproliferative Syndrome
Intervention:   Genetic: Genomic profiling
Sponsors:   Dana-Farber Cancer Institute;   Charles H. Hood Foundation

HypErsensitiVity PneumonITis: DiseAse Progression Characterization

Condition:   Hypersensitivity Pneumonitis
Intervention:   Other: Disease assessment
Sponsors:   Hospital do Coracao;   Boehringer Ingelheim
Not yet recruiting