Precision Health Clinical Trials
Biomarker Identification in Orthopaedic & Oral Maxillofacial Surgery Subjects to Identify Risks of Bisphosphonate Use
Conditions: Osteoporosis, With or Without Treatment; Bisphosphonate Treatment; Atypical Femur Fracture; Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ); Healthy Volunteers
Intervention:
Sponsor: University of Pennsylvania
Recruiting
Intervention:
Sponsor: University of Pennsylvania
Recruiting
For more information, visit the Study URL.
Use Massive Parallel Sequencing and Exome Capture Technology to Sequence the Exome of Fanconi Anemia Children and Their Patents
Conditions: Fanconi Anemia; Autosomal or Sex Linked Recessive Genetic Disease; Bone Marrow Hematopoiesis Failure, Multiple Congenital Abnormalities, and Susceptibility to Neoplastic Diseases.; Hematopoiesis Maintainance.
Interventions: Genetic: human whole exome; Genetic: whole genomic
Sponsor: Xiaofan Zhu
Available
Interventions: Genetic: human whole exome; Genetic: whole genomic
Sponsor: Xiaofan Zhu
Available
For more information, visit the Study URL.
Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations
Conditions: Advanced Ovarian Cancer; Primary Peritoneal Cancer; Advanced Breast Cancer; Advanced Solid Tumors
Intervention: Drug: BMN 673
Sponsor: National Cancer Institute (NCI)
Recruiting
Intervention: Drug: BMN 673
Sponsor: National Cancer Institute (NCI)
Recruiting
For more information, visit the Study URL.
Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)
Condition: Hypertension
Intervention:
Sponsor: National Human Genome Research Institute (NHGRI)
Recruiting
Intervention:
Sponsor: National Human Genome Research Institute (NHGRI)
Recruiting
For more information, visit the Study URL.
Genome Sequencing of Human Cancer Tissues
Condition: Cancer
Intervention: Other: Cancer Treatment Options
Sponsor: New Mexico Cancer Care Alliance
Recruiting
Intervention: Other: Cancer Treatment Options
Sponsor: New Mexico Cancer Care Alliance
Recruiting
For more information, visit the Study URL.
Alcoholic Hepatitis: A Multicenter, Observational Study by the TREAT Consortium
Condition: Alcoholic Hepatitis
Intervention:
Sponsors: Indiana University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting
Intervention:
Sponsors: Indiana University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting
For more information, visit the Study URL.
Next Generation pErsonalized tX(Therapy) With Plasma DNA Trial-2 in Refractory Solid Tumors (The NEXT-2 Trial)
Conditions: Metastatic Gastrointestinal Cancer; Genitourinary Cancer
Intervention:
Sponsor: Samsung Medical Center
Recruiting
Intervention:
Sponsor: Samsung Medical Center
Recruiting
For more information, visit the Study URL.
Molecular-Guided Therapy for Childhood Cancer
Conditions: Neuroblastoma; Medulloblastoma; Glioma; Ependymoma; Choroid Plexus Neoplasms; Craniopharyngioma; Dysembryoplastic Neuroepithelial Tumor; Meningioma; Primitive Neuroectodermal Tumors (PNETs); Germ Cell Tumors; Rhabdomyosarcoma; Non-rhabdomyosarcoma; Ewings Sarcoma; Osteosarcoma; Wilms Tumor; Renal Cell Carcinoma; Malignant Rhabdoid Tumor; Clear Cell Sarcoma; Liver Tumors
Intervention: Device: Guided Therapy
Sponsors: Giselle Sholler; Translational Genomics Research Institute; Dell, Inc.
Recruiting
Intervention: Device: Guided Therapy
Sponsors: Giselle Sholler; Translational Genomics Research Institute; Dell, Inc.
Recruiting
For more information, visit the Study URL.
Establishment of NAFLD Cohort and Development of Fibrosis Markers
Condition: Fibrosis of Liver
Interventions: Procedure: Liver biopsy; Device: ARFI; Device: SWE; Device: Transient elastography
Sponsor: Seoul National University Boramae Hospital
Recruiting
Interventions: Procedure: Liver biopsy; Device: ARFI; Device: SWE; Device: Transient elastography
Sponsor: Seoul National University Boramae Hospital
Recruiting
For more information, visit the Study URL.
Comprehensive Genomic Analysis in Tissue Samples From Patients With Recurrent or Stage IV Non-small Cell Lung Cancer
Conditions: Recurrent Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer
Interventions: Other: cytology specimen collection procedure; Other: laboratory biomarker analysis
Sponsors: Barbara Ann Karmanos Cancer Institute; National Cancer Institute (NCI)
Recruiting
Interventions: Other: cytology specimen collection procedure; Other: laboratory biomarker analysis
Sponsors: Barbara Ann Karmanos Cancer Institute; National Cancer Institute (NCI)
Recruiting
For more information, visit the Study URL.