Precision Health Clinical Trials
Bacteria and Intestinal Translocation in Surgery (Bandit)
Condition: Surgical Site Infection
Intervention: Other: No intervention
Sponsor: Insel Gruppe AG, University Hospital Bern
Recruiting
Intervention: Other: No intervention
Sponsor: Insel Gruppe AG, University Hospital Bern
Recruiting
For more information, visit the Study URL.
Regional Registry-based Biobank Development and Pharmacogenetic Analysis in Rheumatoid Arthritis
Condition: Rheumatoid Arthritis
Intervention: Other: Biobank creation and Pharmacogenetic analysis
Sponsors: Istituto Ortopedico Rizzoli; Regione Emilia Romagna - Italy within PRU-Liberati project
Recruiting
Intervention: Other: Biobank creation and Pharmacogenetic analysis
Sponsors: Istituto Ortopedico Rizzoli; Regione Emilia Romagna - Italy within PRU-Liberati project
Recruiting
For more information, visit the Study URL.
Genetic Testing for Men With Metastatic Prostate Cancer
Conditions: Metastatic Prostate Carcinoma; Stage IV Prostate Cancer AJCC v8; Stage IVB Prostate Cancer AJCC v8
Interventions: Procedure: Biospecimen Collection; Other: Genetic Counseling; Other: Genetic Testing; Other: Laboratory Biomarker Analysis; Behavioral: Questionnaire
Sponsors: University of Washington; National Cancer Institute (NCI)
Recruiting
Interventions: Procedure: Biospecimen Collection; Other: Genetic Counseling; Other: Genetic Testing; Other: Laboratory Biomarker Analysis; Behavioral: Questionnaire
Sponsors: University of Washington; National Cancer Institute (NCI)
Recruiting
For more information, visit the Study URL.
A Prospective Study to Evaluate the Consistency of Next-Generation Sequencing(NGS)-Panels by Using Malignant Hydrothorax Form NSCLC
Conditions: Malignant Hydrothorax; NSCLC
Intervention: Diagnostic Test: in vitro NGS-panel
Sponsors: Shanghai Chest Hospital; Sinotech Genomics Co., Ltd; Amoy Diagnostics Co., LTD; Guangzhou Burning Rock Medical Examination Institute Co., Ltd.; Geneplus-Beijing Co. Ltd.; Berry Genomics Co., Ltd.
Recruiting
Intervention: Diagnostic Test: in vitro NGS-panel
Sponsors: Shanghai Chest Hospital; Sinotech Genomics Co., Ltd; Amoy Diagnostics Co., LTD; Guangzhou Burning Rock Medical Examination Institute Co., Ltd.; Geneplus-Beijing Co. Ltd.; Berry Genomics Co., Ltd.
Recruiting
For more information, visit the Study URL.
Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies
Conditions: Sarcoma; Endocrine Tumors; Neuroblastoma; Retinoblastoma; Renal Cancer
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting
For more information, visit the Study URL.
ctDNA as a Biomarker for Treatment Response in HNSCC
Condition: Carcinoma, Squamous Cell of Head and Neck
Intervention: Other: Blood draw
Sponsor: The Netherlands Cancer Institute
Recruiting
Intervention: Other: Blood draw
Sponsor: The Netherlands Cancer Institute
Recruiting
For more information, visit the Study URL.
Neoantigen DNA Vaccine in Combination With Nivolumab/Ipilimumab and PROSTVAC in Metastatic Hormone-Sensitive Prostate Cancer
Condition: Metastatic Hormone-Sensitive Prostate Cancer
Interventions: Biological: PROSTVAC-V; Biological: PROSTVAC-F; Drug: Nivolumab; Drug: Ipilimumab; Biological: Neoantigen DNA vaccine; Device: TriGrid Delivery System; Procedure: Tumor biopsy; Procedure: Peripheral blood; Procedure: Fecal samples; Procedure: Leukapheresis
Sponsors: Washington University School of Medicine; Bristol-Myers Squibb; Prostate Cancer Foundation; BJH Foundation; Bavarian Nordic
Recruiting
Interventions: Biological: PROSTVAC-V; Biological: PROSTVAC-F; Drug: Nivolumab; Drug: Ipilimumab; Biological: Neoantigen DNA vaccine; Device: TriGrid Delivery System; Procedure: Tumor biopsy; Procedure: Peripheral blood; Procedure: Fecal samples; Procedure: Leukapheresis
Sponsors: Washington University School of Medicine; Bristol-Myers Squibb; Prostate Cancer Foundation; BJH Foundation; Bavarian Nordic
Recruiting
For more information, visit the Study URL.
Pembrolizumab in MMR-Proficient Metastatic Colorectal Cancer Pharmacologically Primed to Trigger Hypermutation Status
Conditions: Colorectal Neoplasms; Microsatellite Instability
Interventions: Drug: temozolomide (induction),; Biological: pembrolizumab (treatment)
Sponsor: IFOM ETS - The AIRC Institute of Molecular Oncology
Recruiting
Interventions: Drug: temozolomide (induction),; Biological: pembrolizumab (treatment)
Sponsor: IFOM ETS - The AIRC Institute of Molecular Oncology
Recruiting
For more information, visit the Study URL.
Infant Peri-Exposure Prophylaxis to Prevent HIV-1 Transmission by Breastfeeding: Mechanisms & Safety
Condition: Growth and Development
Intervention:
Sponsor: French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
Recruiting
Intervention:
Sponsor: French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
Recruiting
For more information, visit the Study URL.
Gait as Predictor of Dementia and Falls. The Gait and Brain Cohort Study
Conditions: Gait Apraxia; Mild Cognitive Impairment; Subjective Cognitive Impairment; Cerebral Atrophy; Alzheimer Disease; Dementia
Intervention:
Sponsor: Lawson Health Research Institute
Recruiting
Intervention:
Sponsor: Lawson Health Research Institute
Recruiting
For more information, visit the Study URL.