Precision Health Clinical Trials

Evaluation of the Feasibility and Clinical Relevance of Liquid Biopsy in Patients With Suspicious Metastatic Lung Cancer

Condition:   Metastatic Lung Cancer
Intervention:   Diagnostic Test: InvisionFirst® molecular panel
Sponsor:   Centre Leon Berard
Recruiting

DNA Analysis of Discarded Media Drops From the Clinical IVF Cycles

Condition:   Infertility
Intervention:   Diagnostic Test: chromosome numeration of embryos
Sponsor:   Colorado Center for Reproductive Medicine
Recruiting

Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy

Conditions:   Cancer;   Esophagus Squamous Cell Carcinoma;   Squamous Cell Carcinoma of the Head and Neck;   Anal Canal Squamous Cell Carcinoma;   Metastatic Cancer
Intervention:  
Sponsor:   University Health Network, Toronto
Recruiting

Paired Analysis of Sensitivity for Colorectal Cancer Using COLVERA : PASCAL

Condition:   Colorectal Cancer
Intervention:   Other: Blood Draw
Sponsor:   Clinical Genomics Pathology
Recruiting

Colvera for Detection of Disease Recurrence

Condition:   Colorectal Adenocarcinoma
Intervention:   Other: Blood draw (venipuncture)
Sponsor:   Clinical Genomics Pathology
Recruiting

Genetics of Severe Early Onset Epilepsies

Conditions:   Epilepsy;   Epileptic Encephalopathy;   Ohtahara Syndrome;   Infantile Spasms;   Dravet Syndrome;   Malignant Migrating Partial Epilepsy of Infancy;   Early Myoclonic Epileptic Encephalopathy;   PCDH19-related Epilepsy and Related Conditions
Intervention:  
Sponsors:   Boston Children’s Hospital;   Boston Children's Hospital Genomics Pilot
Recruiting

Non Invasive Prenatal Test of Rare Genetic Diseases: Application to Rare Intellectual Disabilities

Condition:   Genetic Disorders in Pregnancy
Intervention:   Diagnostic Test: NIPT Test
Sponsor:   University Hospital, Strasbourg, France
Recruiting

Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease

Conditions:   Sickle Cell;   PKLR Variants;   Adenosine Triphosphate Activities
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Feasibility of Individualized Therapy for Recurrent Glioblastoma

Condition:   Recurrent Glioblastoma
Intervention:   Drug: Individualized therapy
Sponsor:   Jennifer Clarke
Recruiting

Non-Invasive ctDNA Methylation Detection for Lung Nodule Patients

Condition:   Lung Nodule
Intervention:  
Sponsors:   Shanghai Chest Hospital;   Singlera Genomics Inc.
Recruiting

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