Precision Health Clinical Trials

Combining Active and Passive DNA Hypomethylation

Conditions:   Myelodysplastic Syndromes;   Acute Myeloid Leukemia;   Chronic Myelomonocytic Leukemia
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: Placebo
Sponsors:   Kirsten Grønbæk;   Van Andel Institute - Stand Up To Cancer Epigenetics Dream Team;   Karolinska University Hospital;   Skane University Hospital;   Sahlgrenska University Hospital, Sweden;   University of Southern California;   Imperial College London;   University of Copenhagen;   Zealand University Hospital;   Aalborg University Hospital;   Odense University Hospital;   Technical University of Denmark;   Aarhus University Hospital;   Uppsala University Hospital
Recruiting

For more information, visit the Study URL.

Granzyme A in Patients With E. Coli Bacteremic Urinary Tract Infections

Conditions:   Bloodstream Infection;   Sepsis;   Pathogenesis;   Escherichia Coli Bacteremia
Intervention:  
Sponsor:   Instituto de Investigación Sanitaria Aragón
Not yet recruiting

For more information, visit the Study URL.

2000 HIV Human Functional Genomics Partnership Program

Condition:   HIV Infections
Intervention:  
Sponsors:   Radboud University;   ViiV Healthcare;   Elisabeth-TweeSteden Ziekenhuis;   Erasmus Medical Center;   Onze Lieve Vrouwe Gasthuis
Not yet recruiting

For more information, visit the Study URL.

Irritable Bowel Syndrome and Control Volunteers: Diet Challenge

Condition:   IBS - Irritable Bowel Syndrome
Intervention:  
Sponsors:   Indiana University;   National Institutes of Health (NIH)
Not yet recruiting

For more information, visit the Study URL.

Probiotic for Osteoarthritis

Condition:   Osteoarthritis of Multiple Joints
Intervention:   Other: Probiotic product
Sponsor:   Fondazione Don Carlo Gnocchi Onlus
Not yet recruiting

For more information, visit the Study URL.

Interest of High-throughput Sequencing of RNAs for the Diagnosis of Heterogeneous Genetic Diseases

Conditions:   DNA Sequencing;   Diagnosis of Genetic Diseases of Heterogeneous Origin
Intervention:   Genetic: RNA sequencing
Sponsor:   University Hospital, Strasbourg, France
Not yet recruiting

For more information, visit the Study URL.

Probiotic for Pain Osteoarthritis

Condition:   Osteoarthritis of Multiple Joints
Interventions:   Dietary Supplement: Experimental group;   Dietary Supplement: Control group;   Other: Usual medical care
Sponsor:   Fondazione Don Carlo Gnocchi Onlus
Not yet recruiting

For more information, visit the Study URL.

M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability

Conditions:   Colon Adenocarcinoma;   High-Frequency Microsatellite Instability;   Metastatic Malignant Solid Neoplasm;   Rectal Adenocarcinoma;   Refractory Colorectal Carcinoma;   Stage IV Colon Cancer AJCC v8;   Stage IV Rectal Cancer AJCC v8;   Stage IVA Colon Cancer AJCC v8;   Stage IVA Rectal Cancer AJCC v8;   Stage IVB Colon Cancer AJCC v8;   Stage IVB Rectal Cancer AJCC v8
Intervention:   Biological: Anti-PD-L1/TGFbetaRII Fusion Protein M7824
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)
Recruiting

For more information, visit the Study URL.

Study on Predictiors and Mechanism of Conversion to Psychosis in Individuals at Ultra-high Risk Group

Condition:   Schizophrenia
Intervention:  
Sponsors:   Second Xiangya Hospital of Central South University;   Sun Yat-sen University
Recruiting

For more information, visit the Study URL.

ANDDI-PRENATOME - Feasibility Study for a " Fast " Pangenomic High Throughput Sequencing Analysis in Prenatal Diagnosis

Conditions:   Prenatal;   Genome-wide High Throughput Sequencing
Interventions:   Biological: Invasive fetal sampling, blood sampling of mother and father;   Biological: blood sampling from the mother to recover the circulating cell free fetal DNA;   Other: Parent interviews (optional organizational study);   Other: parent questionnaire (optional organizational study);   Other: professional interviews (optional organizational study);   Other: Focus group for professionals (optional organizational study)
Sponsor:   Centre Hospitalier Universitaire Dijon
Recruiting

For more information, visit the Study URL.

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