Precision Health Clinical Trials

Evaluation Interest of the Circulating Tumor DNA Dosage in Patient With Hepatic Metastatic Uveal Melanoma Candidate to Complete Resection (ct DNA R0)

Condition:   Uveal Melanoma
Intervention:   Biological: Blood sampling
Sponsor:   Institut Curie

Natural History of and Specimen Banking for People With Tumors of the Central Nervous System

Conditions:   Brain Cancer;   Brain Tumor;   Spine Cancer;   Spine Tumor;   Neoplasm
Sponsor:   National Cancer Institute (NCI)

Ontario-wide Cancer TArgeted Nucleic Acid Evaluation

Conditions:   Breast Cancer;   Lung Cancer;   Colorectal Cancer;   Melanoma;   Gynecological Cancer;   Genitourinary Cancer;   Pancreatobiliary Cancer;   Gastrointestinal Cancer;   Head and Neck Cancer;   Rare Cancer;   Unknown Primary Cancer
Sponsors:   University Health Network, Toronto;   Princess Margaret Hospital, Canada

Vaginal and Urinary Microbiome Trial

Conditions:   Atrophic Vaginitis;   Menopause;   Recurrent Urinary Tract Infections
Interventions:   Drug: Premarin vaginal cream;   Drug: Apricot kernel oil
Sponsor:   University of Louisville

Identification of Epigenetic Markers Common to Obesity and Alzheimer's Disease in Women

Conditions:   Obesity;   Alzheimer's Disease
Intervention:   Procedure: Blood sample
Sponsor:   Central Hospital, Nancy, France
Not yet recruiting

The Drug Rediscovery Protocol (DRUP Trial)

Conditions:   Cancer;   Tumors;   Neoplasm;   Neoplasia
Interventions:   Drug: Panitumumab;   Drug: Olaparib;   Drug: Dabrafenib;   Drug: Nilotinib;   Drug: Trametinib;   Drug: Erlotinib;   Drug: Trastuzumab and Pertuzumab (combination treatment);   Drug: Vemurafenib and Cobimetinib (combination treatment);   Drug: Vismodegib;   Drug: Regorafenib;   Drug: Nivolumab;   Drug: Afatinib;   Drug: Dabrafenib and trametinib;   Drug: Ribociclib;   Drug: Lenvatinib;   Drug: Pembrolizumab;   Drug: Durvalumab;   Drug: Rucaparib;   Drug: Axitinib;   Drug: Palbociclib;   Drug: Crizotinib;   Drug: Sunitinib;   Drug: Cabozantinib;   Drug: Abemaciclib;   Drug: Alectinib;   Drug: Atezolizumab and Bevacizumab;   Drug: Ipilimumab and nivolumab;   Drug: Entrectinib;   Drug: Talazoparib;   Drug: Dacomitinib;   Drug: Lorlatinib;   Drug: Erdafitinib;   Drug: Alpelisib
Sponsors:   The Netherlands Cancer Institute;   Amgen;   AstraZeneca;   Bayer;   Bristol-Myers Squibb;   Novartis;   Roche Pharma AG;   Merck Sharp & Dohme LLC;   Boehringer Ingelheim;   Ipsen;   Eisai Inc.;   Pfizer;   Clovis Oncology, Inc.;   Eli Lilly and Company;   Janssen, LP

Concordance of Inivata Liquid Biopsy With Standard of Care Tissue Testing

Condition:   Non-Small Cell Lung Cancer
Sponsors:   Inivata;   Vector Oncology

Salt-sensitive Hypertension Study in Lantian County

Condition:   Hypertension
Intervention:   Dietary Supplement: salt
Sponsor:   First Affiliated Hospital Xi'an Jiaotong University
Not yet recruiting

Glucose Metabolism in Sickle Cell Disease

Conditions:   Sickle Cell Disease;   Diabetes Mellitus
Sponsor:   University of Illinois at Chicago

Urinary Circulating Tumor DNA Detection in Non-small Cell Lung Cancer: a Prospective Study

Conditions:   Carcinoma;   Non-small-cell Lung Cancer;   Lung Neoplasms
Sponsors:   Peking University People's Hospital;   San Valley Biotechnology Incorporated
Not yet recruiting