Precision Health Clinical Trials

Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation and Liver Transplantation.

Condition:   Transplantation
Intervention:  
Sponsors:   Southern Medical University, China;   Third Affiliated Hospital, Sun Yat-Sen University;   181 Central Hospital of the Chinese PLA
Recruiting

For more information, visit the Study URL.

Human Papillomavirus and Cervical Dysplasia in Women With Cystic Fibrosis

Condition:   Cystic Fibrosis
Intervention:   Procedure: Pap smear test and HPV test
Sponsors:   Hospices Civils de Lyon;   Vaincre la Mucoviscidose
Recruiting

For more information, visit the Study URL.

Trabectedin Combined With Durvalumab in Patients With Advanced Pretreated Soft-tissue Sarcomas and Ovarian Carcinomas.

Conditions:   Ovarian Carcinoma;   Soft Tissue Sarcoma
Intervention:   Drug: Combination of trabectedin with durvalumab
Sponsors:   Institut Bergonié;   AstraZeneca;   PharmaMar
Recruiting

For more information, visit the Study URL.

African Severe Asthma Program: A Research Network for Characterisation of Severe Asthma in Africans (ASAP)

Condition:   Severe Asthma
Intervention:  
Sponsor:   Makerere University
Recruiting

For more information, visit the Study URL.

Clinical Sequencing of Cancer and Tissue Repository: OncoGenomics

Conditions:   Neoplasms;   Adenomatous Polyposis Coli;   Neurofibroma, Plexiform;   Myelodysplastic Syndromes
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

For more information, visit the Study URL.

McLean and Genomind Prospective Study

Conditions:   Major Depressive Disorder;   PTSD
Interventions:   Genetic: Phlebotomy - Folate;   Genetic: Cheek Swab;   Other: Self-report surveys
Sponsors:   Mclean Hospital;   Genomind, LLC
Recruiting

For more information, visit the Study URL.

P53 Mutational Status and cf HPV DNA for the Management of HPV-associated OPSCC

Conditions:   Carcinoma, Squamous Cell;   Head and Neck Neoplasms;   Oropharyngeal Neoplasms
Interventions:   Radiation: Intensity Modulated Radiotherapy (IMRT) - deintensified;   Radiation: Intensity Modulated Radiotherapy (IMRT) - standard;   Drug: Cisplatin (or alternative) - deintensified;   Drug: Cisplatin (or alternative) - standard;   Procedure: Assessment for surgical evaluation
Sponsor:   UNC Lineberger Comprehensive Cancer Center
Recruiting

For more information, visit the Study URL.

Validation and Refinement of Noninvasive Diagnostic Biomarkers for Endometriosis, The ENDOmarker Protocol

Condition:   Endometriosis
Intervention:  
Sponsors:   Yale University;   Augusta University;   Penn State University;   University of California, San Francisco;   University of North Carolina;   University of Oklahoma;   University of Pennsylvania;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting

For more information, visit the Study URL.

Profiling of Oncology Patients as Part of Clinical Care and Research

Condition:   Gynecologic Cancer
Intervention:  
Sponsor:   University of Auckland, New Zealand
Recruiting

For more information, visit the Study URL.

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

Condition:   Malignant Peripheral Nerve Sheath Tumors
Intervention:  
Sponsors:   Washington University School of Medicine;   Boston's Children Hospital
Recruiting

For more information, visit the Study URL.

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