Precision Health Clinical Trials

Impact of Diffuse Myocardial Fibrosis on the Ventricular Function in Regurgitant Left-Sided Valve Heart Diseases ( The DIFFUsE Study)

Condition:   Valve Heart Diseases
Interventions:   Device: Cardiac MRI;   Biological: blood samples;   Procedure: myocardial biopsy;   Genetic: blood samples
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting

For more information, visit the Study URL.

Gene Discovery Core, The Manton Center

Conditions:   Undiagnosed Conditions;   Rare Disorders;   Orphan Diseases
Intervention:  
Sponsor:   Boston Children's Hospital
Recruiting

For more information, visit the Study URL.

Validation of a Clinical Screening Grid for Syndromic Schizophrenia

Condition:   Schizophrenia
Intervention:   Genetic: Array comparative genomic hybridization
Sponsors:   Hôpital le Vinatier;   Hospices Civils de Lyon
Recruiting

For more information, visit the Study URL.

Pharmacogenomic Profiling of Pediatric Patients

Conditions:   Mental Disorders;   Metabolism Medication Toxicity;   Pediatric Disorder
Intervention:  
Sponsor:   University of Alabama at Birmingham
Recruiting

For more information, visit the Study URL.

Evaluation of Survival Prognostic Factors for Patients With Exocrine Pancreatic Cancer Resectable or Potentially Resectable

Condition:   Pancreatic Cancer
Intervention:   Other: Additional biological samples
Sponsors:   Centre Hospitalier Universitaire de Besancon;   Cancéropôle Grand-Est
Recruiting

For more information, visit the Study URL.

Identification of Biomarkers That Are Predictive of Early Ibrutinib Treatment Failure in High Risk TP53 Mutated Chronic Lymphocytic Leukemia

Condition:   Chronic Lymphocytic Leukemia
Intervention:   Drug: Ibrutinib
Sponsor:   Oncology Institute of Southern Switzerland
Recruiting

For more information, visit the Study URL.

Acute Kidney Injury Genomics and Biomarkers in TAVR Study

Conditions:   Acute Kidney Injury;   Renal Insufficiency, Chronic;   Heart Failure;   Myocardial Infarction;   Arrhythmias, Cardiac;   Stroke
Intervention:   Procedure: Transcatheter Aortic Valve Replacement
Sponsor:   University of Texas Southwestern Medical Center
Recruiting

For more information, visit the Study URL.

Genomic Translation for Amyotrophic Lateral Sclerosis Care

Condition:   ALS
Intervention:  
Sponsors:   Columbia University;   ALS Association;   Biogen
Recruiting

For more information, visit the Study URL.

Follow-up of a National Cohort of Melanoma Stage IV and Unresectable Stage III Patients

Condition:   Malignant Melanoma
Interventions:   Other: Biological;   Other: Tissular;   Other: Quality of life
Sponsors:   Assistance Publique - Hôpitaux de Paris;   National Cancer Institute (NCI)
Recruiting

For more information, visit the Study URL.

Clinical and Genetic Study of Familial Sarcoidosis (SARCFAM)

Condition:   Sarcoidosis
Intervention:   Genetic: Genetic analysis by SANGER and WHOLE EXOME NEXT GENERATION SEQUENCING
Sponsor:   Hospices Civils de Lyon
Recruiting

For more information, visit the Study URL.

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