Precision Health Clinical Trials

Medico-economic Evaluation of Different High-throughput Sequencing Strategies in the Diagnosis of Patients With Intellectual Deficiency

Condition:   Intellectual Deficiency
Interventions:   Biological: blood samples from children;   Biological: blood samples from parents
Sponsor:   Centre Hospitalier Universitaire Dijon
Recruiting

For more information, visit the Study URL.

Phages Dynamics and Influences During Human Gut Microbiome Establishment

Condition:   Human Gut Microbiome Development
Intervention:   Other: collection of diapers with fresh stools
Sponsors:   Institut Pasteur;   City of Orsay
Recruiting

For more information, visit the Study URL.

The PRognostic Effect of Environmental Factors in Crohn's and Colitis

Conditions:   Inflammatory Bowel Diseases;   Crohn Disease;   Ulcerative Colitis
Intervention:  
Sponsors:   University of Edinburgh;   University of Aberdeen;   The Wellcome Trust Sanger Institute;   NHS Lothian;   Chief Scientist Office of the Scottish Government;   Crohn's and Colitis in Childhood;   Cure Crohn's and Colitis;   Edinburgh and Lothain Health Fund (Lothian Health Board)
Recruiting

For more information, visit the Study URL.

Phenomics and Genomics of Clozapine Pharmacotherapy

Condition:   Schizophrenia Spectrum and Other Psychotic Disorders
Intervention:   Other: Blood is obtained, mostly during routine venipuncture
Sponsor:   Jurjen Luykx
Recruiting

For more information, visit the Study URL.

The Role of Epigenetic Modifications in Autism Spectrum Disorder

Condition:   Autism Spectrum Disorder
Interventions:   Genetic: DNA methylation and Real-time Polymerase Chain Reaction Analysis;   Diagnostic Test: Gilliam Autism Rating Scale Arabic version
Sponsor:   Assiut University
Not yet recruiting

For more information, visit the Study URL.

Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer

Conditions:   Cigarette Smoker;   Current Smoker;   Lung Adenocarcinoma;   Squamous Cell Lung Carcinoma;   Stage IV Non-Small Cell Lung Cancer
Interventions:   Other: Best Practice;   Procedure: Biospecimen Collection;   Other: Laboratory Biomarker Analysis;   Other: Medical Chart Review;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Behavioral: Smoking Cessation Intervention
Sponsor:   Ohio State University Comprehensive Cancer Center
Recruiting

For more information, visit the Study URL.

Detection of Tumor DNA in Blood Samples From Patients With Early Stage Cancer and "Healthy Controls"

Condition:   Neoplasms, Non-hematologic - Stage I-III
Intervention:  
Sponsor:   Lexent Bio, Inc.
Recruiting

For more information, visit the Study URL.

Evaluation of the NantHealth GPS Cancer Test in Patients With Advanced Cancers

Conditions:   Pancreatic Cancer;   Metastatic Breast Cancer;   Metastatic Lung Cancer;   Metastatic Colon Cancer;   Metastatic Melanoma;   Metastatic Prostate Cancer
Intervention:   Diagnostic Test: NantHealth GPS Cancer Test
Sponsors:   Cota Inc.;   Blue Cross Blue Shield;   NantHealth Inc.
Recruiting

For more information, visit the Study URL.

Genomic Sequencing in Patients With HCM Undergoing Septal Myectomy

Conditions:   Hypertrophic Cardiomyopathy;   Genetic Disease;   Gene Product Sequence Variation
Intervention:   Genetic: Genomic sequencing
Sponsor:   The Cleveland Clinic
Recruiting

For more information, visit the Study URL.

Genomics and Epigenomics for New Insights in fEmale OAB (GENIE) Study

Conditions:   Overactive Bladder;   Insulin Resistance
Intervention:  
Sponsor:   Duke University
Recruiting

For more information, visit the Study URL.

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