Precision Health Clinical Trials

Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation and Liver Transplantation.

Condition:   Transplantation
Intervention:  
Sponsors:   Southern Medical University, China;   Third Affiliated Hospital, Sun Yat-Sen University;   181 Central Hospital of the Chinese PLA
Recruiting

Genomics and Epigenomics for New Insights in fEmale OAB (GENIE) Study

Conditions:   Overactive Bladder;   Insulin Resistance
Intervention:  
Sponsor:   Duke University
Recruiting

Genomic Sequencing in Patients With HCM Undergoing Septal Myectomy

Conditions:   Hypertrophic Cardiomyopathy;   Genetic Disease;   Gene Product Sequence Variation
Intervention:   Genetic: Genomic sequencing
Sponsor:   The Cleveland Clinic
Recruiting

Evaluation of the NantHealth GPS Cancer Test in Patients With Advanced Cancers

Conditions:   Pancreatic Cancer;   Metastatic Breast Cancer;   Metastatic Lung Cancer;   Metastatic Colon Cancer;   Metastatic Melanoma;   Metastatic Prostate Cancer
Intervention:   Diagnostic Test: NantHealth GPS Cancer Test
Sponsors:   Cota Inc.;   Blue Cross Blue Shield;   NantHealth Inc.
Recruiting

Detection of Tumor DNA in Blood Samples From Patients With Early Stage Cancer and "Healthy Controls"

Condition:   Neoplasms, Non-hematologic - Stage I-III
Intervention:  
Sponsor:   Lexent Bio, Inc.
Recruiting

McLean and Genomind Prospective Study

Conditions:   Major Depressive Disorder;   PTSD
Interventions:   Genetic: Phlebotomy - Folate;   Genetic: Cheek Swab;   Other: Self-report surveys
Sponsors:   Mclean Hospital;   Genomind, LLC
Recruiting

P53 Mutational Status and cf HPV DNA for the Management of HPV-associated OPSCC

Conditions:   Carcinoma, Squamous Cell;   Head and Neck Neoplasms;   Oropharyngeal Neoplasms
Interventions:   Radiation: Intensity Modulated Radiotherapy (IMRT) - deintensified;   Radiation: Intensity Modulated Radiotherapy (IMRT) - standard;   Drug: Cisplatin (or alternative) - deintensified;   Drug: Cisplatin (or alternative) - standard;   Procedure: Assessment for surgical evaluation
Sponsor:   UNC Lineberger Comprehensive Cancer Center
Recruiting

Genetics of Ehlers-Danlos Syndrome

Conditions:   Genetics Syndrome;   Ehlers-Danlos Syndrome
Intervention:   Diagnostic Test: Genotyping
Sponsor:   Boston University
Recruiting

Composition and Collection Feasibility of Gut Microbiota in Children With and Without Obesity

Condition:   Childhood Obesity
Intervention:  
Sponsor:   University of Illinois College of Medicine at Peoria
Recruiting

Prospective Cohort Study for Lymphoma: Samsung Lymphoma Cohort Study III

Conditions:   Lymphoma, Non-Hodgkin;   Lymphoma, Hodgkin
Intervention:   Drug: Chemotherapy
Sponsors:   Samsung Medical Center;   Samsung Genomic Institute
Recruiting

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