Precision Health Clinical Trials

Study Assessing Risk Factors for Abdominal Pain in Children With Inflammatory Bowel Disease

Condition:   Inflammatory Bowel Disease
Interventions:   Genetic: Genomic DNA;   Genetic: RNA analysis;   Genetic: Microbiome;   Other: Calprotectin;   Other: Pain questionnaires;   Other: Anxiety/Depression Questionnaires
Sponsor:   Connecticut Children's Medical Center
Recruiting

Prospective Biobanking Study in Ovarian, Breast and Head and Neck Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE)

Conditions:   Ovarian Cancer;   Triple-Negative Breast Cancer;   Head and Neck Cancer
Interventions:   Procedure: Tumor biopsies / Tumor surgery;   Procedure: Blood withdrawal
Sponsor:   Institut Curie
Recruiting

Does the Human Gut Microbiome Serve as a Novel Personalized Therapeutic Target for Coronary Atherosclerosis?

Condition:   Coronary (Artery) Disease
Intervention:   Other: coronary artery disease
Sponsors:   Rabin Medical Center;   Weizmann Institute of Science
Not yet recruiting

Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Conditions:   Stomach Neoplasms;   Stomach Cancer;   Familial Cancer;   Fundic Gland Polyposis;   Li-Fraumeni Syndrome;   Lynch Syndrome;   Peutz-Jeghers Syndrome
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Recruiting

Network Of Clinical Research Studies On Craniosynostosis, Skull Malformations With Premature Fusion Of Skull Bones

Condition:   Craniosynostosis
Interventions:   Other: Craniosynostosis Network Environmental Survey;   Other: 2D/3D Photography;   Procedure: Buccal Swab Cell Sampling;   Procedure: Blood sampling;   Procedure: Skin Biopsy;   Procedure: Tissues from a Clinically Indicated Procedure;   Procedure: Pre-operative CT Scan Image Files.
Sponsors:   Icahn School of Medicine at Mount Sinai;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting

Detection of CSF Next Generation Sequencing in the Application of Brain Metastases From Lung Adenocarcinoma or Meningeal Metastasis

Condition:   Recruitment
Intervention:  
Sponsor:   Shandong Cancer Hospital and Institute
Not yet recruiting

Clinical Sequencing of Cancer and Tissue Repository: OncoGenomics

Conditions:   Neoplasms;   Adenomatous Polyposis Coli;   Neurofibroma, Plexiform;   Myelodysplastic Syndromes
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting

African Severe Asthma Program: A Research Network for Characterisation of Severe Asthma in Africans (ASAP)

Condition:   Severe Asthma
Intervention:  
Sponsor:   Makerere University
Recruiting

Trabectedin Combined With Durvalumab in Patients With Advanced Pretreated Soft-tissue Sarcomas and Ovarian Carcinomas.

Conditions:   Ovarian Carcinoma;   Soft Tissue Sarcoma
Intervention:   Drug: Combination of trabectedin with durvalumab
Sponsors:   Institut Bergonié;   AstraZeneca;   PharmaMar
Recruiting

Human Papillomavirus and Cervical Dysplasia in Women With Cystic Fibrosis

Condition:   Cystic Fibrosis
Intervention:   Procedure: Pap smear test and HPV test
Sponsors:   Hospices Civils de Lyon;   Vaincre la Mucoviscidose
Recruiting

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