Precision Health Clinical Trials

Impact of Diffuse Myocardial Fibrosis on the Ventricular Function in Regurgitant Left-Sided Valve Heart Diseases ( The DIFFUsE Study)

Condition:   Valve Heart Diseases
Interventions:   Device: Cardiac MRI;   Biological: blood samples;   Procedure: myocardial biopsy;   Genetic: blood samples
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting

For more information, visit the Study URL.

Gene Discovery Core, The Manton Center

Conditions:   Undiagnosed Conditions;   Rare Disorders;   Orphan Diseases
Intervention:  
Sponsor:   Boston Children's Hospital
Recruiting

For more information, visit the Study URL.

Evaluation Interest of the Circulating Tumor DNA Dosage in Patient With Hepatic Metastatic Uveal Melanoma Candidate to Complete Resection (ct DNA R0)

Condition:   Uveal Melanoma
Intervention:   Biological: Blood sampling
Sponsor:   Institut Curie
Recruiting

For more information, visit the Study URL.

Clinical and Genetic Study of Familial Sarcoidosis (SARCFAM)

Condition:   Sarcoidosis
Intervention:   Genetic: Genetic analysis by SANGER and WHOLE EXOME NEXT GENERATION SEQUENCING
Sponsor:   Hospices Civils de Lyon
Recruiting

For more information, visit the Study URL.

Follow-up of a National Cohort of Melanoma Resectable Stage II, Stage III or IV Patients or Unresectable Primary

Condition:   Malignant Melanoma
Interventions:   Other: Biological;   Other: Tissular;   Other: Quality of life
Sponsors:   Assistance Publique - Hôpitaux de Paris;   National Cancer Institute (NCI)
Recruiting

For more information, visit the Study URL.

Genomic Translation for Amyotrophic Lateral Sclerosis Care

Condition:   ALS
Intervention:  
Sponsors:   Columbia University;   ALS Association;   Biogen
Recruiting

For more information, visit the Study URL.

Acute Kidney Injury Genomics and Biomarkers in TAVR Study

Conditions:   Acute Kidney Injury;   Renal Insufficiency, Chronic;   Heart Failure;   Myocardial Infarction;   Arrhythmias, Cardiac;   Stroke
Intervention:   Procedure: Transcatheter Aortic Valve Replacement
Sponsor:   University of Texas Southwestern Medical Center
Recruiting

For more information, visit the Study URL.

Identification of Biomarkers That Are Predictive of Early Ibrutinib Treatment Failure in High Risk TP53 Mutated Chronic Lymphocytic Leukemia

Condition:   Chronic Lymphocytic Leukemia
Intervention:   Drug: Ibrutinib
Sponsor:   Oncology Institute of Southern Switzerland
Recruiting

For more information, visit the Study URL.

Evaluation of Survival Prognostic Factors for Patients With Exocrine Pancreatic Cancer Resectable or Potentially Resectable

Condition:   Pancreatic Cancer
Intervention:   Other: Additional biological samples
Sponsors:   Centre Hospitalier Universitaire de Besancon;   Cancéropôle Grand-Est
Recruiting

For more information, visit the Study URL.

Pharmacogenomic Profiling of Pediatric Patients

Conditions:   Mental Disorders;   Metabolism Medication Toxicity;   Pediatric Disorder
Intervention:  
Sponsor:   University of Alabama at Birmingham
Recruiting

For more information, visit the Study URL.

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