Precision Health Clinical Trials

Clinic, Pathologic and Genetic Characterization of Patients With Familial Carcinoid Tumors (Study From the GTE, Groupe d'étude Des Tumeurs Endocrines)

Condition:   Small Intestinal Carcinoid Tumors
Intervention:   Genetic: Research of constitutional genetic alterations
Sponsor:   CHU de Reims
Not yet recruiting

CFI-400945 in Patients With Advanced/Metastatic Breast Cancer

Condition:   Breast Cancer
Intervention:   Drug: CFI-400945
Sponsors:   Canadian Cancer Trials Group;   Stand Up To Cancer Canada-Canadian Cancer Society Breast Cancer Dream Team
Not yet recruiting

Study of the Physiology of Pre-eclampsia and Vascular IUGR With Constitution of a Biological Collection

Condition:   Pre-Eclampsia
Intervention:   Other: collect of placenta, blood and urinary samples at delivery
Sponsor:   Centre Hospitalier Intercommunal Creteil

Non-invasive Prenatal Diagnosis of Monogenic Disorders by Linked-reads Technology

Condition:   Cystic Fibrosis
Sponsor:   University Hospital, Brest
Not yet recruiting

Exploration of DNA Methylation as a Marker for Early Detection of High Grade Serous Epithelial Ovarian Cancer

Condition:   Epithelial Ovarian Cancer
Intervention:   Other: DNA Methylation
Sponsor:   Baylor Research Institute
Not yet recruiting

Genomic and Proteomic Study of Richter Syndrome (CGPSR)

Condition:   Richter Syndrome
Interventions:   Genetic: Whole exome sequencing.;   Genetic: RNA sequencing;   Other: Mass spectrometry
Sponsors:   Central Hospital, Nancy, France;   French Innovative Leukemia Organization (FILO);   Institut National de la Santé Et de la Recherche Médicale, France

Identifying MSI Status From ctDNA in Chinese Patients With Refractory Advanced Solid Tumors

Condition:   Solid Tumor
Intervention:   Diagnostic Test: SPANOM (identifying MSI status from ctDNA)
Sponsor:   Peking University

Detection of MSI in ctDNA of Colorectal Carcinoma Patients

Conditions:   Microsatellite Instability;   Stage IV Colorectal Cancer AJCC v8;   Stage IVA Colorectal Cancer AJCC v8;   Stage IVB Colorectal Cancer AJCC v8;   Stage IVC Colorectal Cancer AJCC v8
Interventions:   Procedure: Biospecimen Collection;   Procedure: Serial Liquid Biopsy
Sponsors:   University of Southern California;   National Cancer Institute (NCI)
Not yet recruiting

Bloodstream Infection Due to Multidrug-Resistant Organisms - Multicenter Study on Determinants of Clinical Outcomes

Conditions:   Bloodstream Infection;   Septic Shock
Sponsors:   University Hospital Tuebingen;   University Hospital Freiburg;   University Hospital Lübeck;   University Hospital of Berlin;   University of Giessen;   Universitätsklinikum Köln

Snack Foods and Their Impact on Gastrointestinal Microbiology, Function and Symptoms

Conditions:   Human Microbiome;   Eating Behavior
Interventions:   Dietary Supplement: Intervention snack 1;   Dietary Supplement: Intervention snack 2;   Dietary Supplement: Control snack
Sponsors:   King's College London;   Queen Mary University of London;   University of Liverpool