Precision health is continuing to expand in Arizona. The University of Arizona Health Sciences and Banner Health have been selected as a key member of the National Institute of Health Precision Medicine Initiative Cohort Program, receiving a $4 million grant on July 6, 2016, part of a five-year $43.3 million grant. The goal of the Precision Medicine Initiative Cohort Program is to enroll 1 million people in the US to fuel research that will improve treatment and prevention of disease based on an individual’s unique genetic makeup, environment, and lifestyle. The University of Arizona Health Sciences and Banner Health are uniquely positioned to promote inclusion of individuals from American Indian, Alaska Native, and Hispanic/Latino populations. This contribution to the Precision Medicine Initiative Cohort Program will improve the representation of these individuals in these studies, and make the medical advances spurred by this initiative available to all populations, regardless of race, ethnicity, or geography.