Precision Health Clinical Trials

Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients

Condition:   Solid, Liquid, Central Nervous System Tumors
Interventions:   Other: Study Introduction Visit;   Other: Informed Consent Visit;   Other: Informed Consent Follow-Up Visit;   Other: Return of Results Conversation;   Other: Return of Results Follow-Up Visits;   Procedure: Blood Sample;   Procedure: Skin Biopsy
Sponsor:   St. Jude Children's Research Hospital
Recruiting

For more information, visit the Study URL.

Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases

Conditions:   Spinal Muscular Atrophy;   Charcot-Marie-Tooth Disease;   Muscular Dystrophy;   Spinal Muscular Atrophy With Respiratory Distress 1;   Amyotrophic Lateral Sclerosis;   Motor Neuron Disease;   Neuromuscular Disease;   Peroneal Muscular Atrophy
Intervention:   Other: sample collection
Sponsor:   Nemours Children's Clinic
Recruiting

For more information, visit the Study URL.

Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and Adrenoleukodystrophy

Conditions:   Metachromatic Leukodystrophy;   Adrenoleukodystrophy
Intervention:   Genetic: transduced CD34+ hematopoietic stem cell
Sponsors:   Shenzhen Second People's Hospital;   Shenzhen University;   Guangzhou Women and Children's Medical Center
Recruiting

For more information, visit the Study URL.

Whole Genome Sequencing for Blood Group Genotyping and Definition as Exemplified on U- and St(a)+.

Condition:   Genetic Blood Group (bg) Polymorphism in U Negativity and St(a) of MNSs
Intervention:   Other: Whole Genome Sequencing (WGS)
Sponsor:   Blood Donation Service Zurich, SRC
Recruiting

For more information, visit the Study URL.

To Study The Influence Of Genomic Factors On Metabolism And Effects Of Clomiphene In Asian Normogonadotrophic Anovulatory Patients.

Condition:   Infertility, Female
Intervention:  
Sponsors:   KK Women's and Children's Hospital;   National Cancer Centre, Singapore
Recruiting

For more information, visit the Study URL.

Genetic Variants of Selected Genes in Colo-Rectal Cancer Patients.

Condition:   Cancer Colon
Intervention:   Genetic: Whole genome sequencing
Sponsors:   Sherief Abd-Elsalam;   Tanta University
Recruiting

For more information, visit the Study URL.

Minimal Residual Disease as a Possible Predictive Factor for Relapse in Patients With AL Amyloidosis

Conditions:   Amyloidosis;   Primary Amyloidosis
Intervention:  
Sponsor:   Tufts Medical Center
Recruiting

For more information, visit the Study URL.

Identification of a Biomarker Associated With Cis-duplication of the SMN1 Gene

Condition:   Spinal Muscular Atrophy
Intervention:   Procedure: blood sampling
Sponsors:   University Hospital, Rouen;   Society GENOMIC VISION
Recruiting

For more information, visit the Study URL.

Protocols Development for Single Cells Genomics and Their Implementation for Molecular Diversity Between Cells

Condition:   Healthy
Intervention:   Other: non
Sponsor:   Hadassah Medical Organization
Not yet recruiting

For more information, visit the Study URL.

Identification of Prognostic Biomarkers for Progression of Invasive Squamous Cell Carcinoma

Conditions:   Carcinoma, Squamous Cell;   Carcinoma, Squamous;   Squamous Cell Carcinoma;   Lung Neoplasms;   Cancer of Lung;   Cancer of the Lung;   Lung Cancer;   Neoplasms, Lung;   Neoplasms, Pulmonary;   Pulmonary Cancer;   Pulmonary Neoplasms
Intervention:   Genetic: DNA Extraction
Sponsor:   Mayo Clinic
Recruiting

For more information, visit the Study URL.

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