Precision Health Clinical Trials

Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD)

Conditions:   Pulmonary Disease, Chronic Obstructive;   Emphysema;   Bronchitis, Chronic
Intervention:  
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Studies of Blood and Reproductive Fluids in HIV-Infected and Non-HIV-Infected Persons

Conditions:   HIV;   Immunodeficiencies
Intervention:  
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Medstar Health Research Institute
Recruiting

Alcoholic Hepatitis: A Multicenter, Observational Study by the TREAT Consortium

Condition:   Alcoholic Hepatitis
Intervention:  
Sponsors:   Indiana University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting

Acute Lymphoblastic Leukemia Therapies Informed by Genomic Analyses

Condition:   Leukemia, Acute Lymphoblastic
Intervention:   Other: Acute Lymphobastic Leukemia (ALL) Treatment Options
Sponsor:   New Mexico Cancer Care Alliance
Recruiting

Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and Adrenoleukodystrophy

Conditions:   Metachromatic Leukodystrophy;   Adrenoleukodystrophy
Intervention:   Genetic: transduced CD34+ hematopoietic stem cell
Sponsors:   Shenzhen Second People's Hospital;   Shenzhen University;   Guangzhou Women and Children's Medical Center
Recruiting

Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases

Conditions:   Spinal Muscular Atrophy;   Charcot-Marie-Tooth Disease;   Muscular Dystrophy;   Spinal Muscular Atrophy With Respiratory Distress 1;   Amyotrophic Lateral Sclerosis;   Motor Neuron Disease;   Neuromuscular Disease;   Peroneal Muscular Atrophy
Intervention:   Other: sample collection
Sponsor:   Nemours Children's Clinic
Recruiting

Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients

Condition:   Solid, Liquid, Central Nervous System Tumors
Interventions:   Other: Study Introduction Visit;   Other: Informed Consent Visit;   Other: Informed Consent Follow-Up Visit;   Other: Return of Results Conversation;   Other: Return of Results Follow-Up Visits;   Procedure: Blood Sample;   Procedure: Skin Biopsy
Sponsor:   St. Jude Children's Research Hospital
Recruiting

To Study the Individual Variants of Chemotherapy-Induced Neurotoxicity

Condition:   Neurotoxicity Syndromes
Interventions:   Other: Questionnaires;   Procedure: Peripheral nervous system examination;   Genetic: Whole Genome Sequence
Sponsor:   National Cheng-Kung University Hospital
Recruiting

Molecular Disease Profile of Hematological Malignancies

Condition:   Hematological Malignancies
Intervention:  
Sponsors:   University of Pavia;   IRCCS Policlinico S. Matteo;   Fondazione Salvatore Maugeri
Recruiting

Genomic Landscape of EGFR Mutant NSCLC Prior to Erlotinib and at the Time of Disease Progression

Conditions:   Carcinoma, Non-Small-Cell-Lung;   Non-Small Cell Lung Cancer;   Nonsmall Cell Lung Cancer
Intervention:  
Sponsor:   Washington University School of Medicine
Recruiting

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