Precision Health Clinical Trials

iCare for Cancer Patients

Conditions:   Myelodysplastic Syndromes;   Acute Myeloid Leukemia;   Acute Myelogenous Leukemia;   Acute Lymphoid Leukemia;   Leukemia, Acute Lymphoblastic;   Multiple Myeloma;   Myelofibrosis
Intervention:   Genetic: Molecular diagnostic testing
Sponsors:   University of Florida;   Cellworks Group Inc.;   Gateway for Cancer Research
Recruiting

Genomic Landscape of EGFR Mutant NSCLC Prior to Erlotinib and at the Time of Disease Progression

Conditions:   Carcinoma, Non-Small-Cell-Lung;   Non-Small Cell Lung Cancer;   Nonsmall Cell Lung Cancer
Intervention:  
Sponsor:   Washington University School of Medicine
Recruiting

Molecular Disease Profile of Hematological Malignancies

Condition:   Hematological Malignancies
Intervention:  
Sponsors:   University of Pavia;   IRCCS Policlinico S. Matteo;   Fondazione Salvatore Maugeri
Recruiting

To Study the Individual Variants of Chemotherapy-Induced Neurotoxicity

Condition:   Neurotoxicity Syndromes
Interventions:   Other: Questionnaires;   Procedure: Peripheral nervous system examination;   Genetic: Whole Genome Sequence
Sponsor:   National Cheng-Kung University Hospital
Recruiting

Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients

Condition:   Solid, Liquid, Central Nervous System Tumors
Interventions:   Other: Study Introduction Visit;   Other: Informed Consent Visit;   Other: Informed Consent Follow-Up Visit;   Other: Return of Results Conversation;   Other: Return of Results Follow-Up Visits;   Procedure: Blood Sample;   Procedure: Skin Biopsy
Sponsor:   St. Jude Children's Research Hospital
Recruiting

Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases

Conditions:   Spinal Muscular Atrophy;   Charcot-Marie-Tooth Disease;   Muscular Dystrophy;   Spinal Muscular Atrophy With Respiratory Distress 1;   Amyotrophic Lateral Sclerosis;   Motor Neuron Disease;   Neuromuscular Disease;   Peroneal Muscular Atrophy
Intervention:   Other: sample collection
Sponsor:   Nemours Children's Clinic
Recruiting

Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and Adrenoleukodystrophy

Conditions:   Metachromatic Leukodystrophy;   Adrenoleukodystrophy
Intervention:   Genetic: transduced CD34+ hematopoietic stem cell
Sponsors:   Shenzhen Second People's Hospital;   Shenzhen University;   Guangzhou Women and Children's Medical Center
Recruiting

Whole Genome Sequencing for Blood Group Genotyping and Definition as Exemplified on U- and St(a)+.

Condition:   Genetic Blood Group (bg) Polymorphism in U Negativity and St(a) of MNSs
Intervention:   Other: Whole Genome Sequencing (WGS)
Sponsor:   Blood Donation Service Zurich, SRC
Recruiting

To Study The Influence Of Genomic Factors On Metabolism And Effects Of Clomiphene In Asian Normogonadotrophic Anovulatory Patients.

Condition:   Infertility, Female
Intervention:  
Sponsors:   KK Women's and Children's Hospital;   National Cancer Centre, Singapore
Recruiting

Genetic Variants of Selected Genes in Colo-Rectal Cancer Patients.

Condition:   Cancer Colon
Intervention:   Genetic: Whole genome sequencing
Sponsors:   Sherief Abd-Elsalam;   Tanta University
Recruiting

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