Precision Health Clinical Trials

Biomarkers for the Surgical Treatment of Rotator Cuff Tears

Condition:   Rotator Cuff Tears
Intervention:  
Sponsors:   Balgrist University Hospital;   RESORTHO foundation, Forchstrasse 340, 8008 Zürich, Switzerland
Recruiting

For more information, visit the Study URL.

Randomized Controlled Trial of Genomically Directed Therapy in Patients With Triple Negative Breast Cancer

Conditions:   Malignant Neoplasm of Breast;   Breast Cancer
Interventions:   Drug: Genomically Directed Monotherapy;   Other: Observation/Standard Therapy
Sponsors:   Bryan Schneider, MD;   Hoosier Cancer Research Network;   Vera Bradley Foundation for Breast Cancer;   Walther Cancer Institute;   Strategic Research Initiative Grant through IUSCC
Recruiting

For more information, visit the Study URL.

Defining the Basis of Fibromuscular Dysplasia (FMD)

Conditions:   Fibromuscular Dysplasia;   Spontaneous Coronary Artery Dissection;   Cervical Artery Dissection
Intervention:  
Sponsor:   Icahn School of Medicine at Mount Sinai
Recruiting

For more information, visit the Study URL.

Study to Determine the Efficacy of Regorafenib in Metastatic Colorectal Cancer Patients and to Discover Biomarkers

Condition:   Metastatic Colorectal Cancer
Intervention:   Drug: Regorafenib
Sponsors:   Gerald Batist;   Bayer;   Quebec Clinical Research Organization in Cancer
Recruiting

For more information, visit the Study URL.

Phase I Study of Olaparib and Temozolomide for Ewings Sarcoma or Rhabdoomyosarcoma

Conditions:   Ewing Sarcoma;   Rhabdomyosarcoma
Interventions:   Drug: Olaparib;   Drug: Temozolomide;   Drug: Irinotecan
Sponsor:   Massachusetts General Hospital
Recruiting

For more information, visit the Study URL.

Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics

Conditions:   Smoking;   Diabetes
Intervention:   Procedure: Dental implant surgery
Sponsors:   University of North Carolina, Chapel Hill;   National Institute of Dental and Craniofacial Research (NIDCR);   National Center for Research Resources (NCRR)
Recruiting

For more information, visit the Study URL.

Collecting and Studying Tissue Samples From Patients With HIV-Associated Malignancies

Conditions:   Lung Cancer;   Lymphoma
Interventions:   Genetic: DNA analysis;   Genetic: RNA analysis;   Genetic: gene expression analysis;   Genetic: polymorphism analysis;   Other: biologic sample preservation procedure;   Other: flow cytometry;   Other: medical chart review
Sponsors:   AIDS Malignancy Consortium;   National Cancer Institute (NCI);   The Emmes Company, LLC;   AIDS and Cancer Specimen Resource;   University of Arkansas
Recruiting

For more information, visit the Study URL.

Molecular Determinants of Coronaruy Artery Disease

Conditions:   Coronary Artery Disease;   Arteriovenous Malformations;   Myocardial Infarction
Intervention:  
Sponsors:   The Cleveland Clinic;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

For more information, visit the Study URL.

Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

Conditions:   Non-Small Cell Lung Cancer;   Small Cell Lung Cancer;   Extrapulmonary Small Cell Cancer;   Pulmonary Neuroendocrine Tumors;   Thymic Epithelial Tumors
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Recruiting

For more information, visit the Study URL.

Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

Conditions:   Stage IIA Lung Cancer AJCC v8;   Stage IIB Lung Cancer AJCC v8;   Stage IIIA Lung Cancer AJCC v8;   Stage IIIB Lung Cancer AJCC v8
Interventions:   Procedure: Biospecimen Collection;   Drug: Carboplatin;   Drug: Cisplatin;   Other: Clinical Observation;   Procedure: Computed Tomography;   Drug: Crizotinib;   Other: Cytology Specimen Collection Procedure;   Drug: Erlotinib;   Drug: Gemcitabine Hydrochloride;   Biological: Nivolumab;   Drug: Paclitaxel;   Biological: Pembrolizumab;   Drug: Pemetrexed;   Drug: Pemetrexed Disodium;   Other: Placebo Administration;   Procedure: Positron Emission Tomography
Sponsor:   National Cancer Institute (NCI)
Recruiting

For more information, visit the Study URL.

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