Official Title
The TOGETHER Project - Transplant Organ Genomics to Help Prevent Rejection in Heart Transplant Recipients
Brief Title
The TOGETHER Project - Heart
Protocol ID
NCT03833050
Lead Sponsor
Mayo Clinic
Brief Summary
The researchers are trying to develop a way to measure the risk of transplant rejection
with a blood test.
Detailed Description
The study will utilize peripheral blood assays collected at time points that are
considered standard of care at most institutions. Subjects will have peripheral blood
collected at 1 month, 3 months, 6 months, and 12 months after heart transplantation, as
well as any for cause time points. These samples will then be used for purposes of
developing an RNA-seq based peripheral blood assay in adult heart transplant recipients.
Study Period
-
Enrollment Count
101 participants
Eligibility Criteria
Inclusion Criteria:
Patients who meet all of the following criteria are eligible for enrollment as study
participants:
- Adult (≥18 years) solitary heart transplant recipient
- Patient is willing and able to provide informed written consent
Exclusion Criteria:
Patients who meet any of these criteria are not eligible for enrollment as study
participants:
- Adult (<18 years) heart transplant recipient
- Patient refusal to enroll in the studyc3. Any simultaneous heart and extra organ
transplant, including pancreas, liver, lung, kidney, etc. Subjects who have had
previous transplants may be included.
Filters
Heart Transplant Rejection
COMPLETED
ADULT
OLDER_ADULT