Official Title
A Study Designed to Develop in Vitro Models of Liver, Biliary and Pancreatic Cancer for the Investigation of Tumour Biology and Potential Therapies
Brief Title
In Vitro Models of Liver and Pancreatic Cancer
Protocol ID
NCT02436564
Lead Sponsor
Cambridge University Hospitals NHS Foundation Trust
Brief Summary
The primary objective is to develop an in vitro model of cancer for laboratory study
using liver, biliary and pancreatic cancer tissue. The secondary objective is to study
the genetic and cellular biology of cancer of the liver, biliary tract and the pancreas.
As well the investigators hope to compare molecular and cellular biology of cancer cells
with normal cells as well as potentially test the efficacy of current and future
anti-cancer therapies.
Samples will be collected from tissue that has been resected as part of the treatment for
a patient diagnosed with liver, bile duct or pancreas cancer.
Enrollment Count
75 participants
Eligibility Criteria
Inclusion Criteria:
- All adult patients undergoing surgical resections for liver, biliary or pancreas
cancers that are able to give informed consent.
Exclusion Criteria:
- Patients aged <18 or those who are unable to give informed consent.
Filters
Cholangiocarcinoma
Hepatocellular Carcinoma
Pancreatic Neoplasm
UNKNOWN
ADULT
OLDER_ADULT