Precision Health Clinical Trials
Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas
Condition: Colonic Neoplasms
Intervention:
Sponsors: University of Michigan Rogel Cancer Center; Early Detection Research Network; Clinical Genomics Pathology; VolitionRx; Department of Health and Human Services; Great Lakes New England Clinical Validation Center; National Cancer Institute (NCI)
Recruiting
Intervention:
Sponsors: University of Michigan Rogel Cancer Center; Early Detection Research Network; Clinical Genomics Pathology; VolitionRx; Department of Health and Human Services; Great Lakes New England Clinical Validation Center; National Cancer Institute (NCI)
Recruiting
For more information, visit the Study URL.
Evaluation ctDNA in Patients of Non-Small-Cell Lung Cancer Following Resection
Condition: Non-Small Cell Lung Cancer
Intervention: Diagnostic Test: Perioperative ctDNA Dynamic Monitoring
Sponsors: Sun Yat-sen University; Hangzhou Repugene Technology Co., Ltd.
Recruiting
Intervention: Diagnostic Test: Perioperative ctDNA Dynamic Monitoring
Sponsors: Sun Yat-sen University; Hangzhou Repugene Technology Co., Ltd.
Recruiting
For more information, visit the Study URL.
Genotypic Influences on Network Progression in Parkinson's Disease
Condition: Parkinson's Disease
Interventions: Genetic: DNA/GeneticTesting; Radiation: FDG PET scan; Other: MRI scan; Other: Clinical and neuropsychological assessments
Sponsors: Northwell Health; Michael J. Fox Foundation for Parkinson's Research; The Silverstein Foundation for Parkinson's with GBA
Recruiting
Interventions: Genetic: DNA/GeneticTesting; Radiation: FDG PET scan; Other: MRI scan; Other: Clinical and neuropsychological assessments
Sponsors: Northwell Health; Michael J. Fox Foundation for Parkinson's Research; The Silverstein Foundation for Parkinson's with GBA
Recruiting
For more information, visit the Study URL.
Uro-DNA Collection for Expanded Genome-Wide Association Study (GWAS) of Renal Cell Carcinoma (RCC)
Condition: Kidney Cancer
Interventions: Procedure: Intervention in the UroCCR sites; Procedure: Intervention in the CRB of Bordeaux University Hospital; Procedure: Intervention at the Methodology and Data Management Centre of Bordeaux University Hospital; Procedure: Subsequent intervention at the NCI (for information)
Sponsors: University Hospital, Bordeaux; National Cancer Institute (NCI)
Recruiting
Interventions: Procedure: Intervention in the UroCCR sites; Procedure: Intervention in the CRB of Bordeaux University Hospital; Procedure: Intervention at the Methodology and Data Management Centre of Bordeaux University Hospital; Procedure: Subsequent intervention at the NCI (for information)
Sponsors: University Hospital, Bordeaux; National Cancer Institute (NCI)
Recruiting
For more information, visit the Study URL.
Development of a Predictive Model for Early Differential Diagnosis of Uterine Leiomyomas and Leiomyosarcomas
Conditions: Leiomyoma; Leiomyosarcoma
Intervention: Procedure: Biopsy and peripheral blood collection
Sponsor: Igenomix
Recruiting
Intervention: Procedure: Biopsy and peripheral blood collection
Sponsor: Igenomix
Recruiting
For more information, visit the Study URL.
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan
Condition: Hearing Disorder
Intervention:
Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting
Intervention:
Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting
For more information, visit the Study URL.
Personalized Medicine Program on Myelodysplastic Syndromes: Characterization of the Patient's Genome for Clinical Decision Making and Systematic Collection of Real World Data to Improve Quality of Health Care
Condition: MDS (Myelodysplastic Syndrome)
Intervention:
Sponsor: Fondazione Italiana Sindromi Mielodisplastiche-ETS
Recruiting
Intervention:
Sponsor: Fondazione Italiana Sindromi Mielodisplastiche-ETS
Recruiting
For more information, visit the Study URL.
FATLAS: Comprehensive Multi-level Characterization of Systemic and Mammary Adiposity in Breast Cancer Patients.
Condition: Breast Neoplasms
Intervention: Other: Prospective data and sample collection
Sponsors: Universitaire Ziekenhuizen KU Leuven; KU Leuven
Recruiting
Intervention: Other: Prospective data and sample collection
Sponsors: Universitaire Ziekenhuizen KU Leuven; KU Leuven
Recruiting
For more information, visit the Study URL.
Analysis of Screen-detected Lung Cancers' Genomic Traits
Condition: Lung Cancer
Intervention:
Sponsor: University College, London
Recruiting
Intervention:
Sponsor: University College, London
Recruiting
For more information, visit the Study URL.
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma
Conditions: Acute Lymphoblastic Leukemia; Acute Lymphoblastic Lymphoma
Interventions: Drug: Prednisone; Drug: Vincristine; Drug: Daunorubicin; Drug: Pegaspargase; Drug: Erwinase®; Drug: Cyclophosphamide; Drug: Cytarabine; Drug: Mercaptopurine; Drug: Dasatinib; Drug: Methotrexate; Drug: Blinatumomab; Drug: Ruxolitinib; Drug: Bortezomib; Drug: Dexamethasone; Drug: Doxorubicin; Drug: Etoposide; Drug: Clofarabine; Drug: Vorinostat; Drug: Idarubicin; Drug: Nelarabine; Drug: Thioguanine; Drug: Asparaginase Erwinia chrysanthemi (recombinant)-rywn; Drug: Calaspargase Pegol
Sponsors: St. Jude Children's Research Hospital; Incyte Corporation; Amgen; Servier
Recruiting
Interventions: Drug: Prednisone; Drug: Vincristine; Drug: Daunorubicin; Drug: Pegaspargase; Drug: Erwinase®; Drug: Cyclophosphamide; Drug: Cytarabine; Drug: Mercaptopurine; Drug: Dasatinib; Drug: Methotrexate; Drug: Blinatumomab; Drug: Ruxolitinib; Drug: Bortezomib; Drug: Dexamethasone; Drug: Doxorubicin; Drug: Etoposide; Drug: Clofarabine; Drug: Vorinostat; Drug: Idarubicin; Drug: Nelarabine; Drug: Thioguanine; Drug: Asparaginase Erwinia chrysanthemi (recombinant)-rywn; Drug: Calaspargase Pegol
Sponsors: St. Jude Children's Research Hospital; Incyte Corporation; Amgen; Servier
Recruiting
For more information, visit the Study URL.