Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Conditions:   Acute Leukemia of Ambiguous Lineage in Relapse;   Acute Myeloid Leukemia, in Relapse;   Refractory Acute Leukemia of Ambiguous Lineage;   Refractory Acute Myeloid Leukemia
Interventions:   Drug: Venetoclax;   Drug: Selinexor;   Drug: Cytarabine;   Drug: Fludarabine;   Biological: Filgrastim;   Drug: Methotrexate;   Drug: methotrexate/hydrocortisone/cytarabine
Sponsors:   St. Jude Children's Research Hospital;   Karyopharm Therapeutics Inc;   AbbVie;   Gateway for Cancer Research
Recruiting